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1.
Neuroradiology ; 61(8): 935-942, 2019 Aug.
Article in English | MEDLINE | ID: mdl-31161261

ABSTRACT

PURPOSE: To evaluate technical success and long-term outcome of CT-guided radiofrequency ablation (RFA) of spinal osteoid osteomas (OO) and osteoblastomas (OB) in six different European centres. METHODS: Eighty-seven patients with spinal OO (77) or OB (10) were treated with CT-guided RFA, after three-dimensional CT-guided access planning. Patient's long-term outcome was assessed by clinical examination and questionnaire-based evaluation including 10-point visual analogue scales (VAS) regarding the effect of RFA on severity of pain and limitations of daily activities. Clinical success was defined as a reduction of > 30% in the VAS score and patient's satisfaction. RESULTS: Overall, RFA was technically successful in 82/87 cases (94.3%) with no major complications; clinical success was achieved in 78/87 cases (89.7%). The OO/OB were localized in the cervical (n = 9/3), the thoracic (n = 27/1), the lumbar (n = 29/4), and the sacral spine (n = 12/2). A decrease in severity of pain after RFA was observed in 86/87 patients (98.9%) with a persistent mean reduction of overall pain score from 8.04 ± 0.96 to 1.46 ± 1.95 (p < 0.001) after a median follow-up time of 29.35 ± 35.59 months. VAS scores significantly decreased for limitations of both daily (5.70 ± 2.73 to 0.67 ± 1.61, p < 0.001) and sports activities (6.40 ± 2.58 to 0.67 ± 1.61, p < 0.001). CONCLUSION: In a multicentric setting, this trial proves RFA to be a safe and efficient method to treat spinal OO/OB and should be regarded as first-line therapy after interdisciplinary case discussion.


Subject(s)
Catheter Ablation , Osteoblastoma/surgery , Osteoma, Osteoid/surgery , Spinal Neoplasms/surgery , Surgery, Computer-Assisted , Adolescent , Adult , Child , Child, Preschool , Cohort Studies , Europe , Female , Humans , Male , Middle Aged , Osteoblastoma/diagnostic imaging , Osteoma, Osteoid/diagnostic imaging , Spinal Neoplasms/diagnostic imaging , Time Factors , Tomography, X-Ray Computed , Treatment Outcome , Young Adult
3.
Semin Musculoskelet Radiol ; 23(1): 3-18, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30699449

ABSTRACT

Chondroid tumors are a heterogeneous group of neoplasms that all share the production of chondroid matrix. This ranges from a fetal type to mature hyaline cartilage and mirrors its imaging characteristics.The benign chondroid tumors represent some of the most encountered incidental bone lesions, with osteochondroma the most frequent benign bone tumor. Enchondroma is mostly asymptomatic, and yet it is probably the second most common primary bone tumor. Similarly, its malignant counterpart, chondrosarcoma, is the second most common malignant primary bone tumor.The 2013 World Health Organization (WHO) updated this group of tumors, and grade 1 chondrosarcoma was renamed "atypical cartilage tumor" and classified as an intermediate type of tumor, not a malignancy, which better describes its clinical behavior.In this article we summarize changes made in the updated 2013 WHO classification and highlight the diagnostic features differentiating an enchondroma from a low-grade chondrosarcoma. We also describe practical imaging aspects of the remaining chondroid tumors.


Subject(s)
Bone Neoplasms/diagnostic imaging , Chondroma/diagnostic imaging , Chondrosarcoma/diagnostic imaging , Incidental Findings , Biopsy , Bone Neoplasms/pathology , Chondroma/pathology , Chondrosarcoma/pathology , Diagnosis, Differential , Humans , Neoplasm Grading
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