[Cardiac diseases related to free radicals and active oxygen species. Pro-oxidation and anti-oxidation in cardiology (part 2)]. / Enfermedades cardíacas relacionadas con los radicales libres y las especies activas del oxígeno. Pro-oxidación y anti-oxidación en cardiología (2a. parte).

In this second part, we study in detail the most important cardiological diseases showing the physiopathological consideration to support the importance of the stationary equilibrium between pro-oxidation and anti-oxidation to maintain the cardiovascular health. Ischemic cardiopathy and its risk factors (lipids, smoke, blood hypertension, alcohol, etc.), anti-oxidation, different cardiac diseases (coronary insufficiency, blood hypertension, congestive heart insufficiency, cardiomyopathies), are analyzed, and finally, we make clear certain information related to the onset of nitrites tolerance phenomenon and its treatment with anti-oxidation products.

[Cardiac diseases related to free radicals and active species of oxygen. Biochemistry (1)]. / Enfermedades cardíacas relacionadas con los radicales libres y las especies activas del oxígeno. Bioquímica (1a. parte).

In the first part of this paper, a group of definitions are explained in order to understand the mechanisms groups of the most important enzymes which participate in the formations of free radicals and active species of oxygen in the heart. Furthermore, we focus on chemistry and the production of these different active species of oxygen, rounding of by giving information related to the importance of hypoxia-reoxygenation, as well as the lipidic peroxidation in the formation of oxygen free radicals. All this information provides us with a biochemical baseline to write a second part about the cardiovascular pathology related to the lack of equilibrium between pro-oxidation and anti-oxidation.