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13.
J Urol ; 123(6): 887-9, 1980 Jun.
Article in English | MEDLINE | ID: mdl-7382007

ABSTRACT

A study was done on 30 patients with advanced adenocarcinoma of the prostate treated with diethylstilbestrol. Three groups of patients were given daily doses of 1, 5, and 1 times 3 mg. diethylstilbestrol, respectively. The study was confined to the effects of treatment on the levels of plasma testosterone by taking hormonal specimens every 4 hours for 24 hours. The results showed little difference of plasma testosterone among the groups under study and a statistical analysis showed no significant differences. Therefore, our study showed no appreciable advantage in the dosage spread over the day, compared to commonly used doses of 1 or 5 mg. diethylstilbestrol given in a single dosage.


Subject(s)
Diethylstilbestrol/administration & dosage , Testosterone/blood , Adenocarcinoma/drug therapy , Diethylstilbestrol/pharmacology , Diethylstilbestrol/therapeutic use , Drug Administration Schedule , Humans , Male , Prostatic Neoplasms/drug therapy
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