The middle ear pressure does not change after adenotonsillectomy in children younger than 10 years old.

OBJECTIVE. In children aged less than 10 years, to assess whether adenotonsillectomy has some permanent or transitory effect on middle ear pressure. MATERIAL AND METHODS. 20 children aged 4 to 9 years old (13 girls and 7 boys) participated in the study. The day before surgery and on days 1, 7, 14 and 21 after adenotonsillectomy both tympanometry and pure tone audiometry were performed. During surgery, medication consisted in dexamethasone, atropine, propofol and sevoflurane. RESULTS. Before surgery, the middle ear pressure was within the range of 0 ± 99 daPa. On day 1 of the followup study, the average right and left middle ear pressure decreased less than -99 daPa in 6 patients aged 4 to 9 years old (2 girls and 4 boys), with a body mass index from 11.9 to 16.6. At day 7 of follow-up, the middle ear pressure increased and none of the patients showed a pressure less than -99 daPa. Before surgery and during the 21 days of follow-up, hearing thresholds were always ≤ 20 dB nHL. No significant difference was observed between children with or without an average middle ear pressure lower than -99 daPa on their age, weight, height, body mass index or duration of the surgery. CONCLUSIONS. After adenotonsillectomy, children aged 4 to 9 years old who received dexamethasone, atropine and sevoflurane might develop negative middle ear pressure with no hearing loss, which may resolve in 1 week. After adenotonsillectomy, in patients with otalgia or risk factors for middle ear disease, closer evaluation of middle ear pressure may be advisable.

Repeatability of static posturography on the follow-up of vestibular rehabilitation.

BACKGROUND AND AIMS: We undertook this study to estimate the limits of agreement of repeated measures of static posturography on healthy adults and to assess the use of those limits on the interpretation of variations observed during vestibular rehabilitation of patients with chronic, peripheral vestibular disease. METHODS: Twenty healthy adults and 30 vestibular patients accepted to participate. At baseline and at weeks 4, 6 and 8 of follow-up, posturography was performed with the eyes open or closed, while adding or not a layer of foam rubber to the base of support. The Dizziness Handicap Inventory was administered to patients prior to rehabilitation and at week 8. RESULTS: At baseline, a difference between groups was observed on the sway area (p < 0.05). Healthy subjects showed no statistical difference among the four recordings (repeatability of measurements from 85-100%). Vestibular patients showed differences among the four recordings on the area and the length/average speed of sway (p <0.05); individual differences from baseline exceeding the limits of agreement were observed on the sway area. A decrease on the Dizziness Handicap Inventory (≥18 points) was observed on 19 patients, from whom 12 (63, 95% CI 53-73%) showed a change on the sway area (eyes closed) that was larger than the limits of agreement. CONCLUSIONS: In healthy subjects, intra-subject repeated recordings of the area and the length/average speed of sway may be reliable at intervals of 4, 6 and 8 weeks. The sway area (without vision) may be a useful sway component, among others, to follow-up vestibular patients with chronic, peripheral disease during rehabilitation.

[Perinatal encephalopathy sequelae identified by a neurobehavioral scale in one year old infants]. / Secuelas de encefalopatía perinatal identificadas con una escala de desarrollo neuroconductual.

OBJECTIVE: to identify neurodevelopmental sequelae in one year old infants with perinatal encephalopathy utilizing the neurobehavioral scale named Vanedela. METHODS: a cohort of 75 newborns with perinatal encephalopathy was assessed with a neurobehavioral follow-up scale at age of 1, 4, 8 and 12 months. A distinction was made between functional, structural and combined encephalopathy. Two groups of neurodevelopmental outcome at one year were identified: with or without sequelae. Nonparametric statistics was used. RESULTS: infants with functional encephalopathy had the best scores, followed by those with structural encephalopathy, while infants with a combined encephalopathy had the lowest scores. At one year of age, the group with neurobehavioral sequelae exhibited the lowest scores and retarded growth. At the same age, the group with functional encephalopathy exhibited no neurobehavioral sequelae, and reached better scores and growth. CONCLUSIONS: the neurobehavioral follow-up scale is able to identify the neurodevelopmental sequelae at the age of one year in infants with perinatal encephalopathy. The application of Vanedela in the clinical field requires of little time, its results are trustworthy and very useful for the neurobehavioral follow-up assessment.

Influence of obesity and gender on the postural stability during upright stance.

OBJECTIVE: To assess the influence of BMI group (lean/overweight/obese) and gender on the postural sway of adults and adolescents during quiet upright stance. METHODS: 90 women and 90 men, aged 12 to 67 years old, accepted to participate. The center of pressure during quiet upright stance was recorded using a force platform, during 4 conditions (eyes open/closed on hard/soft surface). Statistical analysis was performed using multivariate analysis of covariance. RESULTS: During recordings on hard surface, closing the eyes produced a larger increase of sway on obese subjects than on lean and overweight subjects, with a larger increase on the length and the area of sway. Although gender differences were found during the four sensory conditions, no interaction was observed between the BMI group and the gender. These results were not related to the age of the subjects. CONCLUSION: Compared to non-obese subjects, the postural stability of obese subjects may be more vulnerable when vision is not available, with no influence of the gender.

[Peroxisomal D-bifunctional enzyme deficiency. A case report]. / Deficencia enzimática D-bifuncional peroxlsomal. Caso clínico.

Newborn was referred with diagnosis of neonatal epilepsy. Medical team could suspect and confirm D-bifunctional peroxisomal enzymatic deficiency diagnosis. It was made by family antecedents, severe neonatal hypotonia, uncontrolled neonatal seizures, craniofacial dysmorphic features, psychomotor retardation, neuronal migration defect and a positive peroxisomal panel. The full study in skin fibroblasts involved enzyme analysis, complementation studies and DNA analysis. The accumulation of very long chain fatty acids, partial deficiency in phytanic acid oxidation, and abnormal morphology of peroxisomes was consistent with a defect in peroxisomal fatty acid oxidation, involving D-bifunctional protein. It is very important to make a diagnosis of this innate error of metabolism in order to give preconceptional genetic counseling, to identify recurrence risk and to perform mutation analysis for the D-bifunctional protein gene, and to offer the prenatal diagnosis.

[Disability due to auditory and vestibular dysfunction in a specialized care center]. / Discapacidad por enfermedad auditiva y vestibular en un centro de atención especializada.

OBJECTIVE: To assess the frequency and characteristics of the disability associated with hearing loss and vestibular disease in a Specialized Medical Center of the Mexican Social Security Institute. METHODS: 530 patients agreed to participate. They were assessed due to hearing loss (n = 252) and vestibular disease (n = 278), 54% and 50% of them worked. After a clinical evaluation and administration of a symptom questionnaire, they were asked about the frequency and days ofdisability to perform daily life activities related to their audiological or vestibular disease and how often they visited the physician during the last year because of their symptoms. RESULTS: Hearing loss patients visited the physician 1-6 times/ year and 15.8% reported disability. Vestibular patients visited the physician 1-8 times/ year and reported disability more frequently (60.8%) (p < 0.01). Among those who worked, 5% of patients with hearing loss and 51% of patients with vestibular disease stopped working during 1-15 cumulative days for the first group and 1-365 cumulative days for the second group. Spearmnan's correlation coefficient between the evolution of the disease and disability days was -0.14 (p < 0.01) for hearing loss patients and -0.27 (p < 0.01 ) for vestibular disease. CONCLUSION: Vestibular disease is a cause of disability. which can have financial impact on both the patient and the health care system.

Discapacidad por enfermedad auditiva y vestibular en un centro de atención especializada / Disability due to auditory and vestibular dysfunction in a specialized care center

Objetivo: identificar la limitación que en su vida diaria padecen los pacientes evaluados por hipoacusia o enfermedad vestibular en un Centro de Atención Especializada del IMSS. Método: participaron 530 pacientes evaluados por primera vez con hipoacusia (n=252) o enfermedad vestibular (n=278), de los cuales eran económicamente activos 54 y 50% respectivamente. Después de la evaluación especializada y de la administración un cuestionario de síntomas co cleovestibulares, se identificó la frecuencia y número de días de discapacidad relacionados con la hipoacusia o enfermedad vestibular y la frecuencia de consultas médicas durante el último año. Resultados: los pacientes con hipoacusia solicitaron consulta médica 1-6 veces/año y 15.8% informaron discapacidad. Mientras que aquéllos con enfermedad vestibular solicitaron 1-8 consultas e informaron discapacidad con más frecuencia (60.8%) (p < 0.01); de los pacientes económicamente activos 5% con hipoacusia y 51% con enfermedad vestibular había tenido discapacidad laboral, de 115 días acumulados para el primer grupo y de 1 365 días para el segundo grupo. La correlación entre el tiempo de evolución de la enfermedad y los días de discapacidad por hipoacusia fue de r de Spearman -0.14 (p < 0.01) y -0.27 (p < 0.01) por enfermedad vestibular. Conclusión. La enfermedad vestibular produce discapacidad, que puede ser prolongada, con implicaciones económicas tanto para el paciente como para la institución que le otorga la atención médica.

Objective: To assess the frequency and characteristics of the disability associated with hearing loss and vestibular disease in a Specialized Medical Center of the Mexican Social Security Institute. Methods: 530 patients agreed to participate. They were assessed due to hearing loss (n=252) and vestibular disease (n=278), 54% and 50% of them worked. After a clinical evaluation and administration of a symptom questionnaire, they were asked about the frequency and days of disability to perform daily life activities related to their audiological or vestibular disease and how often they visited the physician during the last year because of their symptoms. Results: Hearing loss patients visited the physician 1-6 times/ year and 15.8% reported disability. Vestibular patients visited the physician 1-8 times/ year and reported disability more frequently (60.8%) (p < 0.01). Among those who worked, 5% of patients with hearing loss and 51% of patients with vestibular disease stopped working during 115 cumulative days for the first group and 1 365 cumulative days for the second group. Spearman's correlation coefficient between the evolution of the disease and disability days was -0.14 (p < 0.01) for hearing loss patients and -0.27 (p < 0.01 ) for vestibular disease. Conclusion. Vestibular disease is a cause of disability, which can have financial impact on both the patient and the health care system.