ABSTRACT
BACKGROUND & AIMS: The epidemiology of bone disease in home parenteral nutrition (HPN) is unknown. The aim of this paper is to evaluate the prevalence and severity of reduced bone mineral density (BMD) in long-term HPN. DESIGN: Cross-sectional, multicentre study including patients who within the last 12 months had their BMD assessed by dual-energy-X-ray absorptiometry after at least 6 months of HPN. Data on bone pain and fractures, the primary gastrointestinal diseases, nutritional and rehabilitation status and HPN regimen were reviewed. Both the T-score (no. of SD below mean BMD of young subjects) and the Z-score (no. of SD from normal BMD values corrected for sex and age) were analysed. RESULTS: A T -score <-1 at any site of assessment was observed in 84% of the 165 patients enrolled (Subject(s)
Bone Density
, Bone Diseases/epidemiology
, Parenteral Nutrition, Home/adverse effects
, Absorptiometry, Photon/methods
, Adult
, Age Factors
, Aged
, Aged, 80 and over
, Body Mass Index
, Bone Diseases/classification
, Bone Diseases/diagnosis
, Cross-Sectional Studies
, Female
, Fractures, Bone/epidemiology
, Humans
, Italy/epidemiology
, Male
, Middle Aged
, Prevalence
, Regression Analysis
, Retrospective Studies
