ABSTRACT
OBJECTIVE: Nowadays bioactive glasses are finding increasing applications in medical practice due to their ability to stimulate re-mineralisation. However, they are intrinsically brittle materials and the study of new compositions will open up new scenarios enhancing their mechanical properties and maintaining the high bioactivity for a broader range of applications. This systematic review aims to identify the relationship between the composition of bioactive glasses used in medical applications and their influence on the mechanical and biological properties. METHODS: Various electronic databases (PubMed, Science Direct) were used for collecting articles on this subject. This research includes papers from January 2011 to March 2016. PRISMA guidelines for systematic review and meta-analysis have been used. 109 abstracts were collected and screened, 68 articles were read as relevant articles and a total of 22 papers were finally selected for this study. RESULTS: Most of the studies obtained enhanced mechanical properties and the conservation of bioactivity behaviours; although a lack of homogeneity in the characterization methods makes it difficult to compare data. SIGNIFICANCE: New compositions of bioactive glasses incorporating specific ions and the addition in polymers will be the most important direction for future researches in developing new materials for medical applications and especially for dentistry.
Subject(s)
Biocompatible Materials , Ceramics , DentistryABSTRACT
AIM: To compare the in vitro biocompatibility of Biodentine™ and White ProRoot(®) mineral trioxide aggregate (MTA(®) ) with MG63 osteoblast-like cells and to characterize the cement surface. METHODOLOGY: A direct contact model for MG63 osteoblast-like cells with cements was used for 1, 3 and 5 days. Four end-points were investigated: (i) cement surface characterization by atomic force microscopy (AFM), (ii) cell viability by MTT assay, (iii) protein amount quantification by Bradford assay and (iv) cell morphology by SEM. Statistical analyses were performed by analysis of variance (anova) with a repetition test method. RESULTS: The roughness of the cements was comparable as revealed by AFM analysis. The MTT test for Biodentine™ was similar to that of MTA(®) . Biodentine™ and MTA(®) induced a similar but slight decrease in metabolic activity. The amount of total protein was significantly enhanced at day three (P < 0.05) but slightly decreased at day five for both tested samples. Biodentine™ was tolerated as well as MTA(®) in all cytotoxicity assays. SEM observations showed improvement of cell attachment and proliferation on both material surfaces following the three incubation periods. CONCLUSION: The biocompatibility of Biodentine™ to bone cells was comparable to MTA(®) .
Subject(s)
Aluminum Compounds , Biocompatible Materials , Calcium Compounds , Dental Cements , Dentin , Osteoblasts/cytology , Oxides , Silicates , Cell Line , Drug Combinations , Humans , In Vitro Techniques , Microscopy, Atomic Force , Microscopy, Electron, Scanning , Proteins/analysis , Surface PropertiesABSTRACT
This case report describes the esthetic management of a dental trauma at the first visit and its subsequent treatments to restore the esthetics and function. Today, patients expect adequate esthetics and the ability to confidently smile immediately after the first appointment. In addition, they require that esthetics is maintained throughout the definitive treatment phase as well. After the use of the fractured crown as a temporary replacement crown, an orthodontic extrusion was undertaken to restore the physiological periodontal attachment. The tooth was then splinted for 6 months and at completion of this orthodontic stage, the permanent restoration was fabricated.
Subject(s)
Incisor/injuries , Tooth Crown/injuries , Tooth Fractures/therapy , Tooth Root/injuries , Adult , Combined Modality Therapy , Crowns , Dental Prosthesis Design , Esthetics, Dental , Follow-Up Studies , Humans , Male , Post and Core Technique , Root Canal Therapy , Tooth Movement TechniquesABSTRACT
In 1995, the first dental postgraduate residency programme was established in France. Selection of the applicants was performed by means of a selective national competitive examination among dental students in the final year of the undergraduate studies. The main objective of this 3-year general practice internship was to provide a clinical training for future academic dentists. This study describes the characteristics and the professional outcome of the student population enrolled in this programme. The French internship programme represents a new and welcome modification on the training of future dental academicians and establishes similarities with other programmes in Europe.
