1.
Indian J Pediatr
; 77(3): 316-7, 2010 Mar.
Article
in English
| MEDLINE
| ID: mdl-20091374
ABSTRACT
A 10-yr-old HbE/Beta thalassemia child who developed subacute to chronic occipitotemporal hemorrhagic infarct with smaller chronic infarct with gliotic changes in the left frontal periventricular white matter. Genetic tests showed that patient was positive for HbE and IVS1-5 mutation and was negative for thrombogenic mutations. Hemorrhagic infarct was confirmed by magnetic resonance imaging study. Antigenic levels of Protein C and Protein S were low. Based on these outcomes, it was concluded that Protein C and Protein S deficiency were the causative factor for developing hemorrhagic infarct in the HbE/Beta thalassemia patient.
Subject(s)
Cerebral Hemorrhage/etiology , Cerebral Infarction/etiology , Protein C Deficiency/diagnosis , Protein S Deficiency/diagnosis , beta-Thalassemia/complications , Cerebral Hemorrhage/diagnosis , Cerebral Infarction/diagnosis , Child , Humans , Magnetic Resonance Imaging , Male , Protein C Deficiency/complications , Protein S Deficiency/complications
2.
Clin Appl Thromb Hemost
; 14(1): 118-9, 2008 Jan.
Article
in English
| MEDLINE
| ID: mdl-18160597
