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1.
Lik Sprava ; (1-2): 82-9, 2011.
Article in Russian | MEDLINE | ID: mdl-21954640
2.
Lik Sprava ; (3-4): 71-8, 2011.
Article in Russian | MEDLINE | ID: mdl-22416367

ABSTRACT

We investigated the effectiveness of pioglitazone in the treatment of patients with coronary heart disease in combination with MS. In the conduct of research revealed that the addition to standard therapy in patients with coronary heart disease on the background of metabolic syndrome pioglitazone led to a reliable slight decrease in body weight, BMI, hip circumference, waist their relationship. Receiving pioglitazone also significantly reduces the concentration of immunoreactive insulin and blood glucose levels, significantly altered lipid metabolism, which generally leads to a lower level of systemic inflammation, metabolism and reduces the severity of insulin resistance. This allows you to recommend the inclusion of pioglitazone in complex coronary heart disease and metabolic syndrome.


Subject(s)
Coronary Disease/drug therapy , Hypoglycemic Agents/administration & dosage , Metabolic Syndrome/drug therapy , Thiazolidinediones/administration & dosage , Aged , Amlodipine/administration & dosage , Amlodipine/therapeutic use , Aspirin/administration & dosage , Aspirin/therapeutic use , Atorvastatin , Bisoprolol/administration & dosage , Bisoprolol/therapeutic use , Blood Glucose/analysis , Body Mass Index , Body Weight/drug effects , C-Reactive Protein/analysis , C-Reactive Protein/immunology , Coronary Disease/blood , Coronary Disease/complications , Coronary Disease/immunology , Coronary Disease/physiopathology , Heptanoic Acids/administration & dosage , Heptanoic Acids/therapeutic use , Humans , Hypoglycemic Agents/therapeutic use , Insulin/blood , Insulin Resistance , Isosorbide Dinitrate/administration & dosage , Isosorbide Dinitrate/therapeutic use , Lipid Metabolism/drug effects , Lipid Peroxidation/drug effects , Metabolic Syndrome/blood , Metabolic Syndrome/complications , Metabolic Syndrome/immunology , Metabolic Syndrome/physiopathology , Middle Aged , Pioglitazone , Pyrroles/administration & dosage , Pyrroles/therapeutic use , Thiazolidinediones/therapeutic use , Waist-Hip Ratio
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