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1.
Radiobiologiia ; 31(5): 718-21, 1991.
Article in Russian | MEDLINE | ID: mdl-1745762

ABSTRACT

In experiments with albino rats exposed to microwaves (500 microW/cm2), a model of adaptive immunity was developed by transferring lymphoid cells of exposed animals. The effect of microwave radiation was shown to cause autoimmune disorders that were displayed against the background of the structural and functional disturbances of the hematoencephalic barrier.


Subject(s)
Adaptation, Physiological/radiation effects , Autoimmunity/radiation effects , Microwaves , Adaptation, Physiological/immunology , Animals , Antibody Formation/immunology , Antibody Formation/radiation effects , Autoimmunity/immunology , Blood-Brain Barrier/immunology , Blood-Brain Barrier/radiation effects , Lymphocyte Transfusion , Lymphocytes/immunology , Lymphocytes/radiation effects , Male , Rats , Rats, Inbred F344
3.
Gig Sanit ; (3): 9-11, 1991 Mar.
Article in Russian | MEDLINE | ID: mdl-1885033

ABSTRACT

When studying the immune status of the organism the use of additional exposures allow to clear up the defective character of physiological functions even when overt changes are absent. Altitude chamber hypoxia++, reproduction of allergic reactions of the slow and non-slow types, pathogenic Escherichia infection followed by assessment of virulence factors were used as such a stress under exposure to chemicals, electromagnetic fields of radio frequencies. A model was developed for the determination of safe levels of exposure to environmental factors, which makes it possible to differentiate the damaging and defence action of antibodies on the basis of their influence on the fetus and offspring. The effects of antibodies characterized by the postimplantation mortality of fetuses may be used as a criterion of significance for the organism of shifts in immunological reactivity.


Subject(s)
Air Pollutants/toxicity , Autoantibodies/immunology , Autoimmune Diseases/etiology , Disease Models, Animal , Fetal Death/etiology , Hypoxia/immunology , Lung/immunology , Animals , Autoimmune Diseases/immunology , Autoimmune Diseases/prevention & control , Female , Fetal Death/immunology , Fetal Death/prevention & control , Fetus/immunology , Guinea Pigs , Hypoxia/etiology , Hypoxia/prevention & control , Lung/drug effects , Pregnancy , Rats
5.
Gig Sanit ; (3): 11-4, 1989 Mar.
Article in Russian | MEDLINE | ID: mdl-2744497

ABSTRACT

The study was undertaken to determine the main laws of setting-up an epidemiological chain "functional state--predisease--disease" and to define causal and effective relation-ships in the system "environment--community health".


Subject(s)
Environmental Health , Environmental Pollutants/adverse effects , Health , Hypersensitivity/etiology , Morbidity , Urban Health , Adolescent , Adult , Child , Epidemiologic Methods , Humans , Research , Ukraine
11.
Radiobiologiia ; 26(5): 705-8, 1986.
Article in Russian | MEDLINE | ID: mdl-3774988

ABSTRACT

In experiments on albino Wistar rats the autoimmune reactions were shown to be stimulated by the effect of microwaves of 50 and 500 microW/cm2. The authors showed the possibility of the autoimmunity simulation by immunization of intact animals by the brain tissue of exposed albino rats. This process was dependent on the microwave radiation intensity.


Subject(s)
Autoantibodies/biosynthesis , Immunity/radiation effects , Microwaves , Animals , Rats , Rats, Inbred Strains
13.
Radiobiologiia ; 25(6): 840-3, 1985.
Article in Russian | MEDLINE | ID: mdl-4081001

ABSTRACT

The authors discuss the possibility of stimulating the autoimmune reactions of the organism by microwave irradiation. The immunochemical analysis of protein fractions of blood serum has revealed a destabilization of functional activity of the immune system humoral factors at 500 W/cm2 which is manifested by the formation of a new protein with the immunoglobulin G physico-chemical properties.


Subject(s)
Antibody Formation/radiation effects , Autoantibodies/biosynthesis , Microwaves , Animals , Female , Immunoelectrophoresis , Male , Rats
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