[Clinico-cytological characteristics of primary invasive cervical cancer]. / Kliniko-tsitologicheskaia kharakteristika nachal'nogo invazivnogo raka sheiki matki.

Based on the material of the complex examination of 167 cervical cancer patients in stage Ia, the clinico-cytological features were studied comparatively. Extensive colposcopy and cytological assays of surface curetting specimens from the cervical canal and cervix mucosa were employed. In cervical cancer, stage Ia, cytological assay in 71.4% of cases is a reliable criterion in diagnosing the malignancy. In 51.7% of patients cytograms are similar to those of intraepithelial cancer, in 40.7%--smears correspond to the classical description of squamous cell cancer. The stromal reaction should be regarded as an indicator of a limited malignancy and as a manifestation of protective forces of the organism.

[Morphologic criteria for the initial forms of stage Ia invasive cancer of the cervix uteri]. / Morfologicheskie kriterii nachal'nykh form invazivnogo raka sheiki matki Ia stadii.

Morphological study was carried out on biopsy and operation materials from 107 patients with initial forms of cervical cancer. The initial forms of cancer include lesions suspect for infiltrative cancer, and infiltrative cancer with the depth of invasion not more than 3 mm. The condition of the stroma in initial invasion which is considered to be a defence reaction is described in detail. In 85% of the patients the infiltrative cancer developed against the background of carcinoma in situ, in 15% against the background of dysplasia. The authors believe that the morphological features of the initial invasive forms are sufficient for distinguishing them as a separate stage Ia.

[Clinical morphological characteristics of the initial forms of cervical cancer]. / Kliniko-morfologicheskaia kharakteristika nachal'nykh form raka sheiki matki

An analysis of clinical and colposcopic findings in 107 patients with early forms of invasive cancer of the uterine cervix with deep invasion not more than 3 mm (st. 1-a) and their correlation with the results of histological assay enabled the authors to give the clinico-morphological characteristics of this stage of the lesion. It was found that 40% of patients had complaints pathognomonic for a malignant process; 91.6% of patients showed visually recognizable but nonspecific changes in the cervix; in 94% of cases colposcopy revealed cancer suspicious changes of the common and increased atypical epithelium type. In 53.3% cancer foci are so limited that these would be removed by primary biopsy. Metastases in regional lymph nodes were detected in 1.6%. Limited foci of the cancer and extremly rare metastases spread in regional lymph nodes justify the use of hysterectomy solely in treatment of such patients.