ABSTRACT
In the experiment on 75 white rats, the reactogenicity and strength of catgut, dexon, kacelon and PGL (native analogue of vicryl) were studied 10, 20 and 30 days after their implantation into parenchyma of the lactating mammary gland (MG). Around a catgut thread, the cellular-tissue reaction according to the type of purulent inflammation occurred. A danger of oncogenic effect of catgut which manifested itself in proliferation and atypical hyperplasia of epithelium of the MG ducts was noted. Dexon, kacelon and PGL were characterized by similar low reactogenicity, but kacelon strength reduced considerably in moistening. Dexon and PGL due to their reactogenicity and strength properties are the materials of choice in surgical treatment of MG diseases.
Subject(s)
Lactation , Mammary Glands, Animal , Sutures , Animals , Female , RatsABSTRACT
The authors suggest a unified system of designation of type--sizes of surgical suture materials of various nature and structure, which removes the existing discrepancy between the numbering of foreign and Soviet threads as well as of Soviet threads produced by different enterprises of the country. Introduction of the new system of metric sizes of the suture threads will allow surgeons to be properly orientated in the choice of the necessary suture material and make easier the work of services engaged in the development and realization of surgical suture materials.
Subject(s)
Surgical Procedures, Operative/standards , Suture Techniques/classification , Sutures/standards , Calibration/standards , Humans , International System of Units/standards , Suture Techniques/standards , USSR , United StatesSubject(s)
Anti-Infective Agents, Local , Sutures , Animals , Drug Evaluation, Preclinical , Microbial Sensitivity Tests , Polypropylenes , Rabbits , Rats , Time FactorsABSTRACT
Effect of some furan compounds--monofurfurilidene acetone (MFA), difurfurilidene acetone (DIFA), furyl alcohol (Fal) and furfurol (Fl)--on peroxidation of unsaturated fatty acids in lipids was studied in subcellular organelles of rat liver cells in vitro. By the rate of inhibition of lipid peroxidation the substances studied were arranged as follows: DIFA--100%, Fal--65%, Fl--27% and MFA--1-2%. The furan derivatives at the concentration 10(-2) M effectively inhibited the lipid peroxidation in subcellular organelles, especially in mitochondrial and microsomal fractions.