ABSTRACT
Concentrating properties of a new adsorbent, active aluminum oxide, towards poliomyelitis virus type III and simian rotavirus are studied using virus contamination of sewage and drinking water. Optimal concentrations of the adsorbent for effective adsorption of both rota- and polioviruses are established (1.5 and 1 g/liter, respectively) at pH typical of sewage and drinking water (7.0-8.5), as well as the optimal time of virus contact with the adsorbent (30 min). Elution conditions are determined: 3% elution agent beef extract and pH 8.5-9.5 are optimal for both viruses. Active aluminum oxide is recommended as an adsorbent for elimination of enteroviruses from water objects.
Subject(s)
Aluminum Oxide/chemistry , Enterovirus/isolation & purification , Intestines/virology , Water Microbiology , Water Supply , Adsorption , Hydrogen-Ion Concentration , Sewage/microbiologyABSTRACT
Experimental and clinical studies showed a number of virus infections to be accompanied by lipidemic disorders. Experimentally, dyslipidemias were found in tick-borne encephalitis (TBE) in mice, rotavirus infection in rabbits, and amyotrophic leukospongiosis in guinea pigs. The possibility of correcting the virus-induced lipidemic disorders with an antiviral drug, lincomycin, was demonstrated in TBE in mice. Dynamic study of the lipidemic status of patients with virus hepatitis A revealed marked dyslipidemia of the atherogenic type which was stable and persisted up to the time of clinical recovery. The data obtained supplement the current concepts concerning the pathogenesis of virus infections.
Subject(s)
Encephalitis, Tick-Borne/complications , Hepatitis A/complications , Hyperlipidemias/etiology , Prion Diseases/complications , Rotavirus Infections/complications , Adult , Animals , Combined Modality Therapy , Disease Models, Animal , Drug Evaluation, Preclinical , Encephalitis, Tick-Borne/blood , Encephalitis, Tick-Borne/drug therapy , Female , Guinea Pigs , Hepatitis A/blood , Hepatitis A/therapy , Humans , Hyperlipidemias/blood , Hyperlipidemias/epidemiology , Lincomycin/therapeutic use , Lipids/blood , Lipoproteins/blood , Male , Mice , Prion Diseases/blood , Rabbits , Risk Factors , Rotavirus Infections/blood , Time FactorsABSTRACT
The influenza epidemic occurring in Minsk in the autumn of 1986 was caused by at least two drift variants of influenza A virus (H1N1 subtype) differing in two antigenic determinants of hemagglutinin from the viruses isolated in previous years (A/USSR/90/77, A/Dunedin/6/83). One of the epidemic drift variants was found to be identical in the antigenic properties of hemagglutinin with the reference A/Taiwan/1/86 virus.
