Long-term cognitive decline prediction based on multi-modal data using Multimodal3DSiameseNet: transfer learning from Alzheimer's disease to Parkinson's disease.

PURPOSE: Monitoring and predicting the cognitive state of subjects with neurodegenerative disorders is crucial to provide appropriate treatment as soon as possible. In this work, we present a machine learning approach using multimodal data (brain MRI and clinical) from two early medical visits, to predict the longer-term cognitive decline of patients. Using transfer learning, our model can be successfully transferred from one neurodegenerative disease (Alzheimer's) to another (Parkinson's). METHODS: Our model is a Deep Neural Network with siamese sub-modules dedicated to extracting features from each modality. We pre-train it with data from ADNI (Alzheimer's disease), then transfer it on the smaller PPMI dataset (Parkinson's disease). We show that, even when we do not fine-tune the filters learnt from the ADNI MRIs, the transferred model's results are satisfying on PPMI. RESULTS: The first main result is that our model provides satisfying long-term predictions of cognitive decline from any pair of early visits, with no fixed time delay between these visits (provided the potential decline has started at the second visit). The second main result is that the prediction performance on Parkinson's dataset (PPMI) reaches an AUC of 0.81 on PPMI after transfer learning from Alzheimer's dataset (ADNI), without even having to re-train the image filters, versus an AUC of 0.72 for the model trained from scratch on PPMI. CONCLUSIONS: First, our model is effective for predicting long-term cognitive decline from only two visits, even with irregular intervals of time. When dealing with neurodegenerative diseases, where patients often miss some control visits, this is an important finding. Second, our model is able to transfer the knowledge learnt from one neurodegenerative disease (Alzheimer's) to another (Parkinson's), when using the same imaging modalities (brain MRI) and different clinical variables. This makes it usable even for diseases that are rare or under-studied.

A Survey on Anti-Spoofing Methods for Facial Recognition with RGB Cameras of Generic Consumer Devices.

The widespread deployment of facial recognition-based biometric systems has made facial presentation attack detection (face anti-spoofing) an increasingly critical issue. This survey thoroughly investigates facial Presentation Attack Detection (PAD) methods that only require RGB cameras of generic consumer devices over the past two decades. We present an attack scenario-oriented typology of the existing facial PAD methods, and we provide a review of over 50 of the most influenced facial PAD methods over the past two decades till today and their related issues. We adopt a comprehensive presentation of the reviewed facial PAD methods following the proposed typology and in chronological order. By doing so, we depict the main challenges, evolutions and current trends in the field of facial PAD and provide insights on its future research. From an experimental point of view, this survey paper provides a summarized overview of the available public databases and an extensive comparison of the results reported in PAD-reviewed papers.