Quantum-coupled borophene-based heterolayers for excitonic and molecular sensing applications.

Borophene (B), with remarkably unique chemical binding in its crystallographic structural phases including anisotropic structures, theoretically has high Young's modulus and thermal conductivity. Moreover, it is metallic in nature, and has recently joined the family of two-dimensional (2D) materials and is poised to be employed in flexible hetero-layered devices and sensors in fast electronic gadgets and excitonic devices. Interfacial coupling helps individual atomic sheets synergistically work in tandem, and is very crucial in controllable functionality. Most of the microscopic and spectroscopic scans reveal surface information; however, information regarding interfacial coupling is difficult to obtain. Electronic signatures of dynamic inter-layer coupling in B/boron nitride (BN) and B/molybdenum disulfide (MoS2) have been detected in the form of distinct peaks in differential current signals obtained from scanning tunneling spectroscopy (STS) and conducting atomic force microscopy (CAFM). These unique sets of observed peaks represent interfacial coupling quantum states. The peaks in the electronic density of states (DOS) obtained via density functional theory (DFT) band structure calculations matched well with the electronic signatures of coupling quantum states. In our calculations, we found that the DOS peak evolves when the component layers are brought to compromised distances. While B/BN exhibits green sensitivity indicating mid-gap formation, B/MoS2 bestows red sensitivity indicating band-gap excitation of MoS2. Molecular detection of methylene blue (MB) based on surface-enhanced Raman spectroscopy (SERS) was carried out with borophene-based hetero-layered stacks as molecular anchoring platforms.

Early versus late institution of plasma exchange therapy in pregnancy induced thrombotic microangiopathy and its effects on clinical outcomes-A case series.

PURPOSE: To look for incidence of pregnancy associated TMA, clinical presentation and impact of early diagnosis and institution of plasma exchange on overall renal outcomes METHODS: -This is a retrospective study among all female patients who presented with acute kidney injury post pregnancy between October 2002 to April 2016 in department of nephrology in a tertiary care hospital in northern India and diagnosed as pregnancy induced TMA. The patient were assessed for duration of onset of renal failure to time of diagnosis of TMA, role of modality of treatment ie plasmpaharesis to outcome. These patients were assessed for complete, partial or no recovery in renal functions at 60 days after admission. RESULTS: Patients whose time of onset of renal failure to a correct diagnosis of TMA was ≤15 days and age less than 30 years was also associated with good prognosis. The patients who received plasma exchange and that to within 72 h of admission had more chances of recovery. CONCLUSIONS: Early diagnosis of disease and early institution of plasma exchange therapy improves renal outcomes in postpartum TMA.