The potential and practical applications of acylated flavonoids.

Flavonoids have many beneficial health effects. However, their practical applications are often strongly limited due to low solubility and stability in lipophilic media. In order to eliminate this drawback, enzymatic acylation with fatty acids has been introduced. Besides altering physico-chemical properties, bioavailability and biological properties of maternal compounds may also be improved. Although the research dealing with flavonoid ester synthesis is a matter of few years, and several aspects need to be clarified, there is a promising prospect of future application of these selectively acylated derivatives in therapy, cosmetics, and dietetic fields.