ABSTRACT
Cytogenetic analysis was performed in five cases of intestinal type gastric carcinoma. Three cases were near-diploid and two others were near-triploid. The chromosomes involved were: #9 (four cases), #8 (three cases), #1, and #7 (two cases each). The nonrandom chromosomal abnormalities included aberrations of chromosome #9 as trisomy or i(9q) or 9p+ marker chromosome and excess of 8q material (i.e., trisomy or i(8q) chromosome). Our results indicate that abnormalities of chromosome #9 are a common feature in a subgroup of intestinal type gastric cancers and that there are common cytogenetic abnormalities in gastric and large bowel cancer.
Subject(s)
Adenocarcinoma/genetics , Chromosome Aberrations , Stomach Neoplasms/genetics , Adenocarcinoma/pathology , Adult , Aged , Chromosomes, Human, Pair 9 , Female , Humans , Karyotyping , Male , Middle Aged , Neoplasms, Unknown Primary/pathology , Pleural Effusion/pathology , Stomach Neoplasms/pathology , TrisomySubject(s)
Brain/cytology , Brain/pathology , Histological Techniques , Humans , Staining and LabelingABSTRACT
The present investigation shows that the capacity of thyrolymphography for demonstrating the morphologic features of various thyroid lesions is not inferior to that of isotope scanning. On the contrary, lymphography is an effective procedure for detecting small nodules that remain undetected by other methods. Contrast medium is more rapidly distributed to lymph nodes in patients with diffuse goiter and also in patients pretreated with Lugol's solution. Finally, it is shown that the contrast medium employed (Lipiodol Ultra Fluid) remains in the lymph nodes for a period of several months.