ABSTRACT
The effects of hydrogen sulfide baths and sulfide-silt mud applications on the abdominal wall were studied in outbred white rats. Heart preparations stained with hematoxylin and eosin were analyzed and the mean numbers of cells expressing Ki-67, Nkx-2.5, and mesenchymal stem cell markers were determined. Hydrogen sulfide balneotherapy promoted the development of blood capillaries in rat hearts and an increased the expression of CD34. A decrease in the regenerative potential of the myocardium was found due to a decrease in the content of proliferating cells and cells expressing CD73, CD90, and CD105, and also due to the absence of cells stained for cardiomyogenic differentiation marker Nkx-2.5.
Subject(s)
Balneology , Heart/drug effects , Hydrogen Sulfide/pharmacology , Animals , Animals, Outbred Strains , Cell Count , Coronary Vessels/anatomy & histology , Coronary Vessels/cytology , Coronary Vessels/drug effects , Heart/anatomy & histology , Immunohistochemistry , Male , Mesenchymal Stem Cells/cytology , Mesenchymal Stem Cells/drug effects , Myocardium/cytology , Myocardium/metabolism , Organ Size/drug effects , RatsABSTRACT
The natural factors of the "Kluchi" resort are successfully used for the medical rehabilitation of the patients suffering from nonspecific pain in the lower back for a long time. The present comprehensive study of the painful psychovegetative status and the level of blood serotonin included 78 patients presenting with lumbar dorsopathy. After the course of the treatment based at the "Kluchi" health resort, the most significant improvement in the patient's condition was documented in the case of the combination of peloid balneotherapy with magnetic laser therapy and application of efthidermum MPE to the lumbar region.
Subject(s)
Anti-Inflammatory Agents/therapeutic use , Health Resorts , Low Back Pain/rehabilitation , Low-Level Light Therapy/methods , Magnetic Field Therapy/methods , Mud Therapy/methods , Administration, Cutaneous , Adult , Aged , Anti-Inflammatory Agents/administration & dosage , Combined Modality Therapy , Female , Humans , Low Back Pain/diagnosis , Low Back Pain/epidemiology , Low Back Pain/etiology , Male , Middle Aged , Ointments , Pain Measurement , RussiaABSTRACT
This paper was designed to report the results of investigations into the therapeutic effectiveness of "Kluchi" sulfate magnesiumcalcium mineral water used to treat 194 patients presenting with chronic acalculous cholecystitis and different types of biliary tract dysfunction. The control group was comprised of 92 patients who took a diet. It was shown, that mineral water "Kluchi" exerted well apparent beneficial action on the motor function of the gallbladder and the sphincter apparatus. Moreover, drinking the mineral water improved colloidal stability of bile. It is concluded that the therapeutic application of "Kluchi" sulfate magnesium-calcium mineral water results in the reduction of bile lihogenicity, produces anti-inflammatory and choleretic effects, and promotes normalization of the motor and tonic condition of the biliary tract.
Subject(s)
Acalculous Cholecystitis/drug therapy , Balneology , Calcium Sulfate/administration & dosage , Magnesium Sulfate/administration & dosage , Mineral Waters/administration & dosage , Acalculous Cholecystitis/metabolism , Acalculous Cholecystitis/physiopathology , Adult , Bile/metabolism , Biliary Tract/metabolism , Biliary Tract/physiopathology , Chronic Disease , Female , Humans , Male , Middle AgedABSTRACT
The objective of the present study was to provide hygienic assessment of hospital wards equipped with the therapeutic sylvinite screens (TSS) and compare the results of the treatment of 80 patients suffering vulgar psoriasis with the use of TSS and without them. The sylvinite screens made it possible to create comfortable microenvironment in the wards and moderately increased the radiation background (0,15+/-0,005 Sv/hour) thereby promoting saturation of the ward atmosphere with aeroions dominated by the light negative particles (491,5+/-14,4 units/cm3). Such healthy environment hadc beneficial effect on the clinical course of the psoriatic process, the state of functional systems of the patients and their quality of life. It is concluded that the introduction of halotherapy in the treatment in patients presenting with vulgar psoriasis makes it possible to achieve clinical remission in 65% of them compared with 20% of the patients given the traditional treatment.
Subject(s)
Brachytherapy/methods , Hygiene/standards , Microclimate , Minerals/therapeutic use , Psoriasis/therapy , Speleotherapy/methods , Adolescent , Adult , Brachytherapy/standards , Combined Modality Therapy , Humans , Middle Aged , Psoriasis/diagnosis , Psoriasis/drug therapy , Psoriasis/psychology , Quality of Life , Skin/drug effects , Skin/radiation effects , Speleotherapy/standards , Young AdultABSTRACT
The results of the present study give evidence of the well-apparent sanation effect of balneotherapy with the use of therapeutic mineral water (MW) extracted at the Klyuchi health resort. Irrigation of the oral cavity with this mineral water was shown to reduce the number of the strains of opportunistic microorganisms and their virulence potential. It is concluded that the proposed method may be recommended for the treatment and prevention of dysbiosis in the oral cavity of the patients presenting with acquired jaw defects.
Subject(s)
Balneology , Health Resorts , Jaw Diseases/therapy , Jaw/injuries , Mineral Waters/administration & dosage , Female , Humans , Jaw/ultrastructure , Jaw Diseases/microbiology , Jaw Diseases/pathology , Male , Mouth/microbiology , Mouth/ultrastructureABSTRACT
Natural therapeutic factors are successfully used at the Klyuchi health resort for the rehabilitation of the patients presenting with dorsopathies. A total of 120 patients with this condition were examined for the evaluation of their algic and psychovegetative status before and after the balneopeloid therapeutic treatment in combination with transcranial electrostimulation of the brain. Serum serotonin levels were measured during the same periods. It was shown that balneopeloid therapy significantly reduced the intensity of pain, the degree of anxiety and depression, expression of vegetative disorders. Simultaneously, the quality of life of the patients markedly improved and blood serotonin level increased. It was shown that beneficial effect of shortened 14 day courses of balneopeloid therapyon the patients presenting with dorsopathies is similar to that of 21 day courses, but the cost effectiveness of the former is much higher.
Subject(s)
Back Pain/rehabilitation , Balneology/methods , Health Resorts , Spinal Diseases/rehabilitation , Adult , Combined Modality Therapy , Female , Humans , Male , Middle Aged , Mud Therapy/methods , Treatment OutcomeABSTRACT
This review is devoted to the challenging problems of balneotherapeutics, such as the mechanisms of antihypertensive balneotherapy and its optimization. The experience of the authors with the practical application of chloride - sodium, iodine - bromide, and hydrogen sulfide mineral baths is analysed in comparison with the literature data. The role, dosage regimen, and duration of balneotherapeutic treatment as well as the effectiveness of its combination with medicamental therapy are considered. The authors hope that the discussion of these issues will be conducive to the solution of problems currently facing modern antihypertensive balneotherapy.
Subject(s)
Balneology/methods , Hypertension/therapy , Female , Humans , Hypertension/physiopathology , MaleABSTRACT
The experiment on 83 rats has provided a rationale for the use of enterosorbents in acute ethanol intoxication. Polysorb reduces the halflife of ethanol, recovers physical fitness in the animals with acute poisoning. The enterosorbents polysorb, litovit, and sapropel have been found to have a corrective effect on the level of the major plasma antioxidant ceruloplasmin in acute ethanol intoxication. Enterosorbents are an effective detoxifying agent in this condition. Examining the mechanisms of toxic action of ethanol allows the most expedient treatment policy to be substantiated in acute poisonings.
Subject(s)
Alcoholic Intoxication/therapy , Benzopyrans/pharmacology , Enterosorption/methods , Ethanol/adverse effects , Acute Disease , Alcoholic Intoxication/blood , Animals , Ceruloplasmin/metabolism , Ethanol/pharmacology , Humic Substances , RatsABSTRACT
A new technique of low-frequency modulated electric current therapy, SCENAR therapy, was used in treatment of 103 patients with duodenal ulcer (DU). The influence of SCENAR therapy on the main clinical and functional indices of a DU relapse was studied. It was shown that SCENAR therapy, which influences disturbed mechanisms of adaptive regulation and self-regulation, led to positive changes in most of the parameters under study. Addition of SCENAR therapy to the complex conventional pharmacotherapy fastened ulcer healing, increased the effectiveness of Helicobacter pylori eradication, and improved the condition of the gastroduodenal mucosa.
Subject(s)
Anti-Ulcer Agents/therapeutic use , Duodenal Ulcer/therapy , Electric Stimulation Therapy/methods , Omeprazole/therapeutic use , Adolescent , Adult , Duodenal Ulcer/metabolism , Duodenal Ulcer/pathology , Female , Follow-Up Studies , Gastric Acid/metabolism , Humans , Hydrogen-Ion Concentration , Intestinal Mucosa/pathology , Male , Middle Aged , Treatment Outcome , Vagus Nerve/physiopathologyABSTRACT
Thirty patients with duodenal ulcer in remission running in combination with gastroesophageal reflux disease (GERD) were divided into two groups. Patients of group 1 received medication (omeprasol 20 mg twice a day, motilium 10 mg 3 times a day) and mineral water Klyuchi (200 ml 3 times a day). Patients of group 2 received the same medication but no mineral water. The efficacy of the treatment was assessed by the data obtained at esophagogastroduodenofibroscopy, morphological study of gastric and esophageal biopsies, 24-h pH-metry of the esophagus and the stomach. The results suggest that the addition of mineral water Klyuchi to standard medication of GERD shortens correction of clinical, endoscopic and morphological manifestations of the disease.
Subject(s)
Calcium Sulfate/therapeutic use , Duodenal Ulcer/therapy , Gastroesophageal Reflux/therapy , Magnesium Sulfate/therapeutic use , Mineral Waters/therapeutic use , Adult , Anti-Ulcer Agents/therapeutic use , Combined Modality Therapy , Domperidone/therapeutic use , Duodenal Ulcer/complications , Esophagoscopy , Female , Gastroesophageal Reflux/complications , Humans , Male , Middle Aged , Omeprazole/therapeutic useABSTRACT
Scanner therapy in the treatment of patients having duodenal ulcer relapse combines high pharmacoeconomic efficiency with safety providing for clinical and endoscopic remission of the disease.
Subject(s)
Complementary Therapies/methods , Duodenal Ulcer/therapy , Electric Stimulation Therapy/methods , Adolescent , Adult , Aged , Complementary Therapies/adverse effects , Complementary Therapies/economics , Electric Stimulation Therapy/adverse effects , Electric Stimulation Therapy/economics , Female , Humans , Male , Middle Aged , Recurrence , Treatment OutcomeABSTRACT
The review presents 69 references of current literature on the problem of gastroduodenal ulcer physiotherapy which has a good potential of impact on gastroduodenal motility, lipid peroxidation, microcirculation, physiological and reparative regeneration of epithelial and glandular cells. The choice of a physiotherapeutic method depends on the disease stage and to a less extent on location of the ulcer defect.
