[Pulmonary aspergillosis in patients with disseminated processes in the lungs]. / Legochnyi aspergillez u bol'nykh s disseminirovannymi protsessami v legkikh.

Sera of 30 patients with disseminated processes in the lungs of various etiology were examined for the presence of specific IgG to antigens of Aspergillus fumigatus (A.f.) and Candida albicans (C.a.) using solid phase enzyme immunoassay. Elevated concentrations of IgG to A. f. and C. a. were found in 6 and 12 patients, respectively. Serodiagnosis was confirmed by a direct detection of the fungi in the bronchi (cytology of the lavage, culturing). It is highly probable that opportunistic fungi may be involved in pulmonary dissemination. Therefore, patients with disseminated pulmonary diseases should be examined for opportunistic fungi.

[Development and use of a method of determination of specific immunoglobulin G based on immunoenzyme analysis in the diagnosis of pulmonary aspergillosis]. / Razrabotka i primenenie metoda opredeleniia spetsificheskogo immunoglobulina G na osnove immunofermentnogo analiza dlia diagnostiki aspergilleza legkikh.

Enzyme-linked immunoassay (ELISA) was employed for determination of specific immunoglobulin G to Aspergillus fumigatus (A.f.). Culture filtrate of A.f. was used as antigen. Optimal conditions of ELISA were found. Serum of 138 asthmatic patients with total IgE level more than 500 PRU/ml were analysed for determining the limits of IgG to A.f. concentrations.

[An evaluation of the efficacy of Beclometh in bronchial asthma patients]. / Otsenka éffektivnosti beklometa u bol'nykh bronkhial'noi astmoi.

Fifteen bronchial asthma patients were followed-up for 6 months. They were administered beclomet-250 in a daily dose 1000 micrograms. The patients' clinical status was characterized by positive changes, ventilation function of the lungs improved. The drug was discovered to produce no suppressive action on adrenal function. Besides, the patients did not develop oropharyngeal candidiasis.