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1.
Urologiia ; (6): 51-57, 2023 Dec.
Article in Russian | MEDLINE | ID: mdl-38156683

ABSTRACT

INTRODUCTION: Recurrent chronic bacterial prostatitis (rCBP) is a hard-to diagnosis-and-treat disease which there is no consensus. A particularly difficult cohort is represented by patients who had COVID-19. The study aimed to evaluate the taxonomic structure and sensitivity to antibacterial drugs of microorganisms verified in expressed prostate secretion (EPS) in rCBP-patients who had COVID-19. MATERIALS AND METHODS: A multicenter, prospective, randomized study was conducted with the inclusion of 52 rCBP patients who had COVID 19, in which the taxonomic structure and susceptibility were studied to antibacterial drugs of microorganisms that were verified and dominated in the EPS. Bacteriological study was carried out using an extended set of selective nutrient media and special cultivation conditions. Antibiotic susceptibility was determined in the taxa of microbiota dominating in the EPS. RESULTS: The mean age of the patients was 34.8+/-5.2 years, the duration of rCBP was 5.7+/-2.3 years. In all patients, various variants of aerobic-anaerobic compositions of microorganisms were recorded in the life cycle. A total of 27 microbiota taxa were isolated. The aerobic cluster was represented by 16 genera and/or species, the anaerobic cluster by 11. When studying antibiotic susceptibility to antibacterial drugs, an increase in antibiotic resistance of the most microorganisms isolated was revealed. CONCLUSIONS: The taxonomic structure of microorganisms in rCBP-patients who had COVID-19 in all cases was characterized by complex and new variants of aerobic-anaerobic associations of microorganisms. When studying the antibiotic susceptibility, multi-resistant and pan-resistant bacteria were identified that is a real threat to this category of patients.


Subject(s)
COVID-19 , Prostatitis , Male , Humans , Adult , Prostatitis/drug therapy , Prostate , Prospective Studies , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use
2.
Tsitol Genet ; 39(4): 20-4, 2005.
Article in Ukrainian | MEDLINE | ID: mdl-16396327

ABSTRACT

Analysis of alcohol-soluble protein (gliadin) patterns of a group of winter common wheat varieties from different breeding centers of Ukraine resulted in identification of six varieties with the rye 1AL/1RS translocation. The line 7086 AR also carries this translocation. The identified 1AL/1RS translocation is similar to that of the variety Amigo in the secalin pattern. The appearance of this translocation in varieties developed in different breeding centers of the forest-steppe of Ukraine indicates its involvement in coadaptive gene associations.


Subject(s)
Chromosomes, Plant/genetics , Genes, Plant , Selection, Genetic , Translocation, Genetic , Triticum/genetics , Chromosome Mapping , Gliadin/genetics , Glutens , Phylogeny , Plant Proteins/genetics , Seasons , Species Specificity , Triticum/classification , Ukraine
3.
Tsitol Genet ; 34(3): 21-7, 2000.
Article in Russian | MEDLINE | ID: mdl-10920857

ABSTRACT

The analysis of adaptability and genetical distances between 12 cytoplasms of Aegilops, Triticum and Haynaldia villosa for three winter wheat genomes showed an existence of genome-plasmon interactions. The plasmons of Ae. variabilis, Ae. cylindrica, Ae. squarrosa var. strangulata, T. dicoccoides appeared to be perspective in practical breeding for adaptability. Interactions are revealed as alteration of productivity and adaptability, and as genetic divergence.


Subject(s)
Adaptation, Physiological/genetics , Genetic Variation/genetics , Genome, Plant , Triticum/genetics , Cytoplasm/genetics , Extrachromosomal Inheritance/genetics , Genetics, Population , Triticum/physiology
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