1.
Biomed Tech (Berl)
; 47 Suppl 1 Pt 1: 176-8, 2002.
Article
in English
| MEDLINE
| ID: mdl-12451808
ABSTRACT
Intraocular miniaturized image transmission systems are developed to restore vision in patients with irreversible destruction of the anterior ocular segment (i.e. chemical burns, explosion trauma, trachoma) and high risk for corneal transplantation, provided that the posterior ocular segment is intact. To ensure safety of such a device biocompatibility tests were conducted. In the present study the effects of light and temperature in various intensities and the toxicity of the implanted materials on neural function in the rabbit retina in-vivo was investigated. All tests give encouraging results concerning the feasibility of intraocular miniaturized image transmission systems.
Subject(s)
Corneal Opacity/rehabilitation , Materials Testing , Microcomputers , Miniaturization/instrumentation , Prostheses and Implants , Sensory Aids , Animals , Corneal Opacity/physiopathology , Equipment Design , Humans , Rabbits , Retina/physiopathology
2.
Lancet
; 353(9162): 1442, 1999 Apr 24.
Article
in English
| MEDLINE
| ID: mdl-10227246
Subject(s)
Piperazines/adverse effects , Retina/drug effects , Animals , Dogs , Humans , Purines , Retina/enzymology , Sildenafil Citrate , Sulfones
3.
Lancet
; 353(9150): 375, 1999 Jan 30.
Article
in English
| MEDLINE
| ID: mdl-9950445