ABSTRACT
18 of 36 consecutive patients with small cell carcinoma of the lung received a combination of chemotherapy (Adriblastin, Oncovin, Cyclophosphamide) and radiotherapy (primary tumor and CNS). This treatment resulted in a response rte of 78%, and in a median survival of 10.6 months ("limited disease" 13 months, "extensive disease" 9 months). Complete remissions were obtained only in 4 of 18 patients, 4 patients of these were long-term survivors (greater than 18 months). Due to heart diseases, age, or poor general condition 18 patients received a milder combination of chemotherapy ("COM", "VP-O-C") and tumor irradiation. The response rate was 66%. Complete remission was achieved in only 2 of 18 patients. The median survival rate was 8.6 ("limited disease" 10.5 months, "extensive disease" 6.0 months). Survival exceeded 18 months in 4 of these patients. The toxicity was mild, the mean cumulative duration of hospitalization was 78 (30-120) days per patient.
Subject(s)
Carcinoma, Bronchogenic/therapy , Carcinoma, Small Cell/therapy , Lung Neoplasms/therapy , Adult , Aged , Antineoplastic Agents/administration & dosage , Carcinoma, Bronchogenic/drug therapy , Carcinoma, Small Cell/drug therapy , Drug Therapy, Combination , Female , Humans , Lung Neoplasms/drug therapy , Male , Middle Aged , Radiotherapy, High-EnergyABSTRACT
It is reported on 76 patients who were operated on due to an adenoma of the prostate and simultaneous cystolithiasis. The bilateral adenomectomy of the prostate is justified in geriatric patients who are endangered by a secondary failure of other organ systems. The mortality of this selected number of patients is high in simultaneous adenomectomy with lithotomy despite progress in operation technique, anaesthesiology and treatment with antibiotics. On the other hand, all bilaterally operated patients survived so that we recommend this procedure in all risk patients.