[Lesions of the vascular endothelium and impairments of haemostatic coagulation in patients with severe craniocerebral trauma]. / Povrezhdenie sosudistogo éndoteliia i narusheniia sistemy reguliatsii agregatnogo sostoianiia krovi u bol'nykh tiazheloi cherepno-mozgovoi travmoi.

Malfunctions of central hemostasis chains, activation of blood coagulation systems and decreased antithrombogenic potentials of vascular walls are typical of craniocerebral trauma at exacerbation. It provokes the onset of the DIC-syndrome in 98.8% of examinees; the below signs are observed in such condition: decreased platelet resistance of vascular walls, increased aggregation activity of platelets, activated coagulation chain of hemostasis and increased blood viscosity. The prognostically unfavorable criteria of coagulopathy in acute craniocerebral trauma are as follows: pathological response of the vascular wall to transitory ischemia observed concurrently with a reduced dynamic FW activity; a persistently low and/or decreased dynamic AT-III activity; decreased fibrinolytic activities of plasma and platelet counts; and persistently higher concentrations and/or higher dynamic concentrations of fibrinogen and soluble fibrin mono-measured complexes (according to coagulation tests). Hemostasis should be corrected with respect to the above hemostasiologic syndromes.

[Epidemiology of chronic obstructive pulmonary diseases]. / Epidemiologiia khronicheskikh obstruktivnykh zabolevanii legkikh.

In this study the epidemiological problems of chronic obstructive pulmonary diseases in the population of the Far North are considered: prevalence of pathology, risk factors and indices of bronchial obstruction are correlated with age, sex, period of living in the North and clinical course of a disease.