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Vopr Pitan ; (2): 21-3, 1980.
Article in Russian | MEDLINE | ID: mdl-7368668

ABSTRACT

The in vitro test of direct granulation of basophils affected by specific antigens (cardial tissue, acid-soluble fraction of collagen, streptococcal allergens) was investigated in the course of treating 41 patients (29 women and 12 men aged from 20 to 50 years) suffering from a little active rheumatic fever. The patients received a complex of therapeutic measures including high-protein diet (130-140 g protein) and drugs (1.5-2.0 g acetylsalicylic acid and 15 mg of prednisolone a day). As a result of the treatment all the patients improved and demonstrated pain relief in the heart region, reduced palpitation, abatement of general weakness and fatigue. At the same time there was a decrease in the reactivity of basophilic leukocytes, shown by less number of degranulated cells in vitro, activated with specific antigens.


Subject(s)
Dietary Proteins/administration & dosage , Immunity, Cellular/drug effects , Neutrophils/immunology , Rheumatic Heart Disease/immunology , Adult , Aspirin/therapeutic use , Basophils/immunology , Female , Humans , Male , Middle Aged , Prednisolone/therapeutic use , Recurrence , Rheumatic Heart Disease/therapy
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