[Model experiments on the effect of IgM- and IgG-antibodies on the reactivity of Treponema pallidum hemagglutination (TPHA)-test]. / Modellversuche zur Wirkung von IgM- und IgG-Antikörpern auf die Reaktivität des Treponema-pallidum-Hämagglutinations(TPHA)-Tests

Fractionated sera of patients in different stages of syphilis were examined comparatively with the TPHA-FTA(IgM)- and FTA(IgG)-test. It was shown that the TPHA-test proved to be convenient for early immunologic diagnosis of syphilis. The TPHA-test includes not only IgG anti-treponemal antibodies but also IgM antibodies. In the early stage of syphilis a reactive result of TPHA-test can be related exclusively on treponemal specific IgM antibodies.