[The effect of ferromagnet particles on the growth of Walker carcinosarcoma 256 in Wistar rats]. / Vliianie ferromagnitnykh chastits na rost kartsinosarkomy Uoker 256 u krys Wistar.

The intravenous injection of ferromagnetic particles (FMP) was studied for its effect on the growth of Walker 256 carcinosarcoma in Wistar rats. The injection of FMP in a dose of 750 mg/kg increased the organism resistance to the tumour development against a background of phagocytic reaction activation in neutrophils. The injection of FMP in a dose up to 2 g/kg inhibited the phagocytic reactions of neutrophils and accelerated the tumour growth. The data obtained evidence that depending on the FMP dose the total reactivity of the organism may either increase or decrease, thus changing, respectively, its resistance to the development of the tumour process.

[The morphofunctional status of the blood during the experimental intravenous administration of ultradispersed ferromagnetic particles]. / Morfofunktsional'nyi status krovi pri vnutrivennom vvedenii ul'tradispersnykh ferromagnitnykh chastits v éksperimente.

In experiments on rats it has been shown that a single infusion of ultradispersed ferromagnetic particles (size from 0.2 to 1 micron) in a dose of 50 mg/kg leads to an increase in hemoglobin level, red blood cell and leucocyte content, to a growth of blood coagulation time and plasma fibrinolytic activity in the animals' blood, as well as to a rise in the level of neutrophil phagocytic reactions. A single infusion of magnetite particles of similar size, in a dose of 50 mg/kg, was not attended by the above changes, except for an increase in the neutrophil functional activity.