[Taste receptor response to sodium chloride and natriuresis in the workers and employees of an industrial enterprise]. / Izuchenie vkusovoi retseptsii k natriiu khloridu i natriiureza u rabochikh i sluzhashchikh promyshlennogo predpriiatiia.

Studied in the course of one-stage epidemiologic survey of 1191 individuals were the threshold of gustatory sensitivity to table salt and nycterine natriuresis, relation of these indices to dietary habits, some risk factors for cardiovascular disorders and clinical parameters. Differing relations were established between gustatory sensitivity to table salt and natriuresis and age and gender of the examinees, the level of blood pressure, aggravated heredity in respect of arterial hypertension, smoking and alcohol abuse, this enabling one to embark upon a differential approach to dietetic correction of salt consumption.

[The content of free amino acids and biogenic amines in the urine of hypertension patients]. / Soderzhanie svobodnykh aminokislot i nekotorykh biogennykh aminov v moche u bol'nykh gipertonicheskoi bolezn'iu.

Contents of free amino acids and some biogenic amines were studied in hypertonic patients at the age of 40-50 years. The study demonstrates quantitative changes in levels of free amino acids and some biogenic amines caused by disorders of protein metabolism. The data obtained may be used for diagnosis of hypertonic diseases.

[The effect of prostenon on the pressor and depressor humoral systems in patients with resistant arterial hypertension]. / Vliianie prostenona na pressornye i depressornye gumoral'nye sistemy u bol'nykh rezistentnoi arterial'noi gipertoniei.

After ineffective combined drug therapy patients with the resistant patterns of arterial hypertension were given 3 to 5 intravenous injections of prostenon (prostaglandin E2) in the total dose 3-5 mg. Prostenon was noted to produce a lasting hypotensive effect in patients with resistant essential hypertension and parenchymatous renal hypertension. The patients manifested favourable changes in the general clinical symptomatology. The antihypertensive effect of prostenon was related to appreciable activation of depressor humoral factors, with activation of pressor humoral factors being less remarkable.

[Thrombocytic hemostasis and the prostaglandin system at early stages of arterial hypertension]. / Trombotsitarnyi gemostaz i sistema prostanoidov na rannikh stadiiakh arterial'noi gipertonii.

In young patients with borderline arterial hypertension the system of pressor and depressor prostaglandins (PG) is activated with maintenance of their physiological proportion. In patients with I stage essential hypertension a considerable rise in the level of PGF2 alpha and thromboxane determines the system imbalance in the direction of the predominance of pressor components. The platelet hemostatic link in I stage essential hypertension is characterized by an increase in platelet aggregation activity which is mediated by the imbalance of the prostacyclin-thromboxane system in the direction to thromboxane.