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Invest Ophthalmol Vis Sci ; 51(11): 6059-65, 2010 Nov.
Article in English | MEDLINE | ID: mdl-20505193

ABSTRACT

PURPOSE: Peripheral refraction is commonly used to infer retinal shape. Because of the different prevalence of myopia in the white compared with East Asian populations, peripheral refraction along the horizontal meridian was compared in white and East Asian young adults with emmetropic, low myopic, and moderately myopic refractive errors. METHODS: Thirty-five white and 37 East Asian subjects were recruited with central refraction between +1.00 DS and -5.50 DS and ≤ -1.50 DC. Central and peripheral noncycloplegic autorefraction was measured along the horizontal meridian at 5° intervals up to ± 35°, and corneal topography maps were also quantified. RESULTS: There were no significant differences between whites and East Asians in peripheral refraction profiles in the emmetrope and low myope groups, which had peripheral myopic and emmetropic refraction, respectively. However, in the moderate myope group, there was a statistically significant difference between whites and East Asians in peripheral refraction, which was generally hyperopic. East Asian moderate myopes had more relative peripheral hyperopia than did whites of similar central refractive error. Corneal shape and power were comparable between white and East Asian subjects in the three refractive groups. CONCLUSIONS: East Asian moderate myopes have a greater degree of relative peripheral hyperopia and hence a more prolate ocular shape than do white subjects of similar central refractive error. Differences in ocular shape may play a role in the greater propensity for East Asians to develop and progress in myopia compared with whites.


Subject(s)
Asian People/ethnology , Emmetropia/physiology , Myopia/ethnology , Refraction, Ocular/physiology , White People/ethnology , Adolescent , Adult , Cornea/pathology , Corneal Topography , Humans , Young Adult
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