ABSTRACT
A. Biemond (1902-1973), professor of neurology at the University of Amsterdam from 1947-1971, was the editor of the Amsterdam student weekly Propria Cures during his student years from 1921-1922. The articles he wrote for this publication were characterised by lavish baroque prose and complicated syntax with many inversions. The tone was overconfident, facetious and ironic. Themes included fellow female medical students and democracy. In later years, Biemond became an outstanding clinician and an enthusiastic teacher. He was also a participant in the doctors' resistance movement during the Second World War.
Subject(s)
Neurology , History, 20th Century , Humans , Netherlands , WarfareSubject(s)
Complementary Therapies , Fees and Charges , Government Agencies , Health Policy , Humans , Netherlands , Public HealthSubject(s)
Animals, Laboratory , Legislation as Topic , Vivisection , Animals , Ethics, Professional , NetherlandsSubject(s)
Motor Neurons/physiology , Muscle Spindles/physiology , Animals , Cats , Neural ConductionSubject(s)
Autonomic Nervous System/physiology , Nobel Prize , England , History of Medicine , Sweden , United StatesSubject(s)
Motor Neurons/physiology , Action Potentials , Animals , Cell Membrane Permeability , Chlorides/metabolism , Feedback , Membrane Potentials , Muscle Contraction , Muscle Spindles/physiology , Neural Pathways/physiology , Potassium/metabolism , Reflex, Monosynaptic , Sodium/metabolism , Spinal Cord/physiology , Synapses , Synaptic Transmission , VertebratesABSTRACT
1. Cholinomimetics, acetylcholine antagonists and some other compounds of pharmacological interest were administered electrophoretically near neurones within the vermal cerebellar cortex of anaesthetized (pentobarbitone) and unanaesthetized (cerveau isolé) cats.2. The neurones were identified by position within the cortex, spontaneous activity, and the responses to afferent and antidromic stimulation.3. Purkinje cells, but neither granule nor basket cells, were excited by cholinomimetics, and the acetylcholine receptors had muscarinic properties. Excitation was often preceded by depression of the spontaneous firing.4. Intravenously administered atropine and dihydro-beta-erythroidine did not depress the synaptic excitation of cerebellar neurones evoked by impulses in mossy, climbing or parallel fibres.5. Acetylcholine is thus unlikely to be an excitatory transmitter within the feline cerebellum, particularly at mossy fibre-granule cell synapses, despite the presence of relatively high levels of acetylcholinesterase within mossy fibre terminals.