Subject(s)
Chondromatosis, Synovial/diagnostic imaging , Wrist Joint , Adolescent , Chondromatosis, Synovial/diagnosis , Chondromatosis, Synovial/surgery , Humans , Male , Radius/diagnostic imaging , Radius/pathology , Range of Motion, Articular , Ulna/diagnostic imaging , Ulna/pathology , UltrasonographyABSTRACT
A patient with dermatomyositis associated with carcinoma was treated with steroids and antibiotics for possible tuberculosis. Autopsy showed an overwhelming diffuse nongranulomatous infection of Mycobacterium tuberculosis involving only the skeletal muscles and one inguinal lymph node. The rare localization of tuberculosis to skeletal muscle in this case is possibly due to steroid immunosuppression and the humoral immune attack on muscle blood vessels that is a part of dermatomyositis.
Subject(s)
Dermatomyositis/microbiology , Muscles/microbiology , Tuberculosis , Aged , Antitubercular Agents/therapeutic use , Dermatomyositis/drug therapy , Dermatomyositis/pathology , Female , Humans , Muscles/pathology , Prednisone/therapeutic use , Tuberculosis/drug therapy , Tuberculosis/pathologyABSTRACT
We describe a patient with leukemic synovitis complicating acute lymphoplastic leukemia. Leukemic cells were identified in the synovial fluid by an indirect immunofluorescent technique using monoclonal antibodies against early B cell antigens. Since focal leukemic lesions may be missed in synovial biopsy specimens, immunocytological analysis of joint fluids may facilitate early diagnosis of leukemic arthritis.
