ABSTRACT
Control of antibiotic resistance of Vibrio cholerae in various areas of the world revealed the characteristic features of the situation and tendencies of antibiotic resistance development in this microbial group. It was shown that though the main part of the El Tor vibrio of the 7th cholera pandemia period was highly sensitive to antibiotics, separate strains with stable plasmid antibiotic resistance were isolated. By the end of the 70s the spread of resistant cholera germs was registered. The antibiotic resistance was due to R factor of the incompatibility group C widely spread among microorganisms of the other groups.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Cholera/microbiology , Vibrio cholerae/drug effects , Cholera/drug therapy , Cholera/prevention & control , Global Health , Humans , Prognosis , R Factors/drug effects , Vibrio cholerae/geneticsABSTRACT
Sensitivity of 500 El Tor vibrio strains isolated from open water reservoirs was studied with respect to 14 antibiotics. Some of the strains markedly differing from the other isolates by the sensitivity levels and the set of the resistance determinants were subjected to a detailed analysis. The problem of distribution of antibiotic resistant strains of the cholera germ is discussed.