ABSTRACT
Findings are that prevalence of COLD among workers of chemical industrial complex in Kemerovo city, who contact organic chemicals, is 1.6 times higher than that among those in contact with irritants and 5.4 times higher than that in reference group. Chemical industry workers develop dysbalance of pro- and antioxidant processes, that is maximal in those contacting organic solvents.
Subject(s)
Air Pollutants, Occupational/adverse effects , Chemical Industry , Pulmonary Disease, Chronic Obstructive/epidemiology , Adult , Aged , Bronchoconstriction/drug effects , Female , Humans , Male , Middle Aged , Prevalence , Pulmonary Disease, Chronic Obstructive/physiopathology , Risk Factors , Siberia/epidemiology , Urban PopulationABSTRACT
The authors studied influence of chemical hazards with various characteristics on bronchial permeability. Workers exposed to organic chemicals demonstrated respiratory complaints and spirometric signs of bronchial obstruction 1.3-1.8 times more frequently. Longer length of service in hazardous conditions is associated with higher occurrence of bronchial obstruction and more intensive changes of lipid peroxidation.
