ABSTRACT
A device for measuring the blood flow volume velocity based on the principle of blood drops count per an unit of time was developed. The device is simple to manufacture, has an appropriate precision, a wide scale of measurements and can continuously record the blood flow dynamics during an experiment.
Subject(s)
Blood Flow Velocity , Blood Volume Determination/instrumentation , Animals , Electronics/instrumentation , Equipment DesignABSTRACT
It has been found in experiments on isolated papillary muscles that cooling of the cat myocardium does not affect the efficacy of Starling's mechanism but decreases the chronoinotropic autoregulation of the heart muscle.
Subject(s)
Cold Temperature , Myocardial Contraction , Animals , CatsABSTRACT
Experiments on papillary muscles of the cat heart have shown that the strength of contraction is a more adequate and sensitive criterion for evaluation of the effects of temperature, distension and contraction rate on myocardial contractility as compared to the strength of contraction. It is concluded that at the basis of the Starling law and chronoinotropic mechanisms there lies the contractility control exercised through changes in the contraction rate.
Subject(s)
Myocardial Contraction , Animals , Cats , Electric Stimulation , In Vitro Techniques , Papillary Muscles/physiology , TemperatureABSTRACT
Dynamics of the parameters of mechanical activity of the frog isolated myocardium was studied under conditions of temperature variations. Within the temperature range of 0-35 degrees C the temperature decrease leads to a rise in the strength of contractions. Meanwhile the velocity of contractions reaches its optimum value at 20 degrees C. The velocity of contractions proved to be a more adequate and sensitive criterion for evaluating the cold effect on contractility than the strength of contractions. From the analysis of the evidence obtained it is concluded that muscle contractility of the heart is depressed on cooling.