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1.
Epilepsy Res ; 193: 107164, 2023 07.
Article in English | MEDLINE | ID: mdl-37187038

ABSTRACT

Epilepsy is a common neurologic disease and presents a major public health problem. Patients with epilepsy have unexpected occurrence of seizures with many triggered by existing triggering factors such as alcohol, stress etc. Other potential triggers include certain weather or atmospheric parameters and local geomagnetic activity. We have analyzed the impact of atmospheric parameters grouped in 6 grouped weather types or weather regimes and the local geomagnetic activity through the K - index. In the prospective study, we analyzed a total of 431 seizures over a 17-month period. In the results obtained, we found that the most severely common weather regime grouped type of weather was radiation and then precipitation regime. It was also found that grouped weather types of weather regimes had more impact on generalized than focal epileptic seizures. Local geomagnetic activity had no direct effect on the occurrence of epileptic seizures. Those results confirm the thesis how the impact of certain external factors is complex and that the further study is required in that respect.


Subject(s)
Epilepsies, Partial , Epilepsy , Humans , Prospective Studies , Epilepsy/epidemiology , Seizures/epidemiology , Weather
2.
Med Sci Monit ; 24: 5123-5131, 2018 Jul 23.
Article in English | MEDLINE | ID: mdl-30036885

ABSTRACT

BACKGROUND In many countries, the number of children hospitalized for alcohol intoxication is increasing. This study analyzed changes in the number of hospitalizations for alcohol intoxication in children aged 0-18 years at the Department of Pediatrics, University Hospital of Split, from 2008 to 2015. MATERIAL AND METHODS Data were collected retrospectively from hospital medical records. Risk groups were classified according to sex, age, drinking habits, and possible benefits of early psychological or psychiatric interventions. Children were divided into 4 age groups: 0-5 years, 6-9 years, 10-13 years, and 14-18 years. Statistics 12.00 was used for statistical analyses, with P-value <0.05 considered as statistically significant. RESULTS Out of 24 651 hospitalized children, 488 were treated for acute intoxication: 36.40% were girls and 63.60% were boys. Among them, 272 children (55.74%) were acutely intoxicated with alcohol, with the average age of 15.95 years and the average blood alcohol concentration of 2.00%. The proportion of children hospitalized for alcohol intoxication decreased from 1.33% in 2008 to 0.75% in 2015. Alcohol intoxications occurred in most cases outside children's homes (92.42%, P=0.001), and on weekends and holidays (81.62%). Among all intoxicated children, 17 children (6.25%) were positive for drugs. A total of 51.29% of children received psychological support (58.59% of girls and 47.09% of boys). CONCLUSIONS In this study, the number of children hospitalized for alcohol intoxication decreased, possibly as a result of preventive, educational, and psychotherapeutic measures or changing drinking habits. Acute alcohol intoxication was most common in the group of children aged 14 to 18 years, and a significant number of these children were positive for drugs, thus, further preventive interventions should be provided.


Subject(s)
Alcoholic Intoxication/epidemiology , Hospitalization/trends , Adolescent , Alcoholism/epidemiology , Blood Alcohol Content , Child , Child, Hospitalized/statistics & numerical data , Child, Preschool , Croatia , Ethanol/adverse effects , Female , Hospitalization/statistics & numerical data , Hospitals, University/statistics & numerical data , Humans , Male , Retrospective Studies
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