[The bacteriologic background and an analysis of the resistance of the agent to antibacterial preparations in patients in the postresuscitation period]. / Bakteriologicheskii peizazh i analiz rezistentnosti vozbuditelei k antibakterial'nym preparatam u bol'nykh, nakhodiashchikhsia v postreanimatsionnom periode.

A total of 6848 bacteriological passages have been performed in 57 patients during postresuscitation period under bacteriological monitoring that included the investigation of different body media twice daily. A microbial pattern has been compiled, typical of a certain intensive care unit, which served the basis for analysis of the resistance of the most widespread agents of pyoseptic complications to antibacterial preparations, with due consideration for the process site. The scheme of antibacterial therapy suggested made it possible to reduce the incidence of those complications due to the increased efficacy of antibacterial therapy in the postresuscitation period.

[The pathogenesis of generalized suppurative-septic complications in patients with eclampsia and massive blood loss of obstetrical origin]. / Patogenez generalizovannykh gnoino-septicheskikh oslozhnenii u bol'nykh s éklampsiei i massivnoi krovopoterei akusherskogo geneza.

Changes in immune status, central hemodynamics, oxygen regimen and endogenous intoxication indexes have been compared in patients with eclampsia combined with blood loss and in patients with isolated blood loss. It has been established that severe septic processes were 1.5 times and lethality was 4 times more frequent in the first group of patients than in patients with isolated blood loss. Generalized septic processes accompany marked secondary immune defects. The main reasons for the immune system damage are circulatory hypoxia and severe endogenous intoxication.

[A computer system for analysis and presentation of the results of studies of the immune status of patients with a profile of resuscitation]. / Komp'iuternaia sistema analiza i otobrazheniia rezul'tatov issledovaniia immunologicheskogo statusa u bol'nykh reanimatsionnogo profilia.

Logical principles for the use of computer technology in the assessment of medical information in intensive care units are outlined. A computer system for the assessment of the results of immune status studies has been presented. The potentials are demonstrated to form the data bank with realization of precedent search function, presentation of information with the help of computer graphics and calculation of highly informative secondary indexes on the basis of primary ones.

[Choice of antibacterial therapy with the use of a computerized consultation system]. / Vybor antibakterial'noi terapii s pomoshch'iu komp'iuternoi konsul'tativnoi sistemy.

The principle for a consulting system ensuring selection of a "theoretically optimal" antibiotic or antibacterial drug combination for the treatment of severe pyo-septic conditions in critically ill patients is described. The system is an addition to an automated case history, which ensures its efficacy. The algorithms are based on the analysis of the literary data and the results of many years of studying microorganisms in infectious foci.