[Hormonal changes shortly after surgery in patients operated for stomach ulcer]. / Gormonalnye izmeneniia u bolnykh v rannie sroki posle operatsii na zheludke po povodu iazvennoi bolezni.

The content of gastrin, pituitary thyrotropin hormone (TTH), the thyroid hormones thyroxin (T4) and triiodothyronine (T3), and 11-OCS in blood serum and the daily catecholamine content in urine were studied in 86 patients in the early periods, 2-4 weeks, after resection of the stomach or selective proximal vagotomy (SPV). The content of gastrin, TTH, T4, and 11-OCS in blood was reduced and catecholamine excretion diminished in patients after gastric resection. After SPV the concentration of gastrin increased and that of TTH reduced. A certain relationship between the clinical course of peptic ulcer and the indices studied was revealed. The application of rehabilitation measures in the early periods after operations on the stomach improves the neuroendocrine regulation in the organism and the functional condition of the alimentary organs.

[Immunological aspects of restorative processes during rehabilitation of patients with peptic ulcer after surgical interventions]. / Immunologicheskie aspekty vosstanovitel'nykh protsessov pri reabilitatsii bol'nykh iazvennoi bolezn'iu posle operativnykh vmeshatel'stv.

The authors studied the immunological and endocrine status of 296 patients in the early periods, in 2-3 weeks, after resection of the stomach or selective proximal vagotomy for complicated peptic ulcer or inefficacy of nonoperative treatment. Imbalance in the cellular and humoral links of immunity was revealed, which was characterized by the presence of the autoimmune component, depression of the T-lymphocyte system and changes of its functional activity, unbalanced regulatory processes of immunocompetent cells, increase of the humoral link of immunity, diminished biological resistance of the organism, which were manifested to an equal degree in patients who underwent various types of operations. A close correlation of immune and endocrine disorders was revealed. Under the effect of rehabilitation measures positive shifts occurred in the disturbed indices of the immune and endocrine systems, which suggests that the application of physical factors promotes processes of natural immunity and the course of restorative and regenerative processes in rehabilitation of patients who underwent an operation.

[Non-medicinal methods of correction of immune disorders in peptic ulcer patients]. / Nemedikamentoznye metody korrektsii immunnykh narushenii u bol'nykh iazvennoi bolezn'iu.

The authors provide the immunological and radioimmunological data on 148 patients suffering from duodenal ulcer different in size. Material alterations were revealed in the cellular and humoral components of immunity and in the pituitary-thyroid system. Based on the investigations carried out it has been shown that natural therapeutic factors, namely mud applications made according to an original method, being mediated via the endocrine system stimulate the cellular component of immunity, reduce the degree of autoaggression, counteract imbalance of the humoral component of immunity, thereby promoting the acceleration of the restorative and regenerative processes in patients suffering from duodenal ulcer.

[The use of physical factors on the neck area in gastric and duodenal peptic ulcer]. / Primenenie fizicheskikh faktorov na vorotnikovuiu oblast' pri iazvennoi bolezni zheludka i dvenadtsatiperstnoi kishki.

Basing on examination of 54 peptic ulcer patients and 62 patients operated on for duodenal ulcer it was shown that collar region is functionally active. In response to physical factors it promotes better regulation of pituitary and thyroid function as shown by radioimmunoassay, thermography and other modern investigating techniques. The findings support administration of physiotherapy on collar region for correction of neurohumoral regulation, trophicity and function of the stomach in ulcer patients.

[Changes in microelement, prostaglandin and cyclic nucleotide levels in the bile of patients at the early periods after cholecystectomy]. / Izmeneniia mikroelementov, prostaglandinov, tsiklicheskikh nukleotidov zhelchi u bol'nykh v rannie sroki posle kholetsistektomi.

The bile content of trace elements, prostaglandins and cyclic nucleotides was measured in 66 patients in the early times (from 2 to 3 weeks) after cholecystectomy. In 60 patients, the content of trace elements was measured in blood serum. The above characteristics were found to correlate with the clinical features of the patients. The relationship was also established between blood serum and bile trace elements, between prostaglandins and cyclic nucleotides.

[Effect of balneological methods on the functional state and endocrine regulation of the stomach and duodenum in patients with duodenal ulcer]. / Vliianie bal'neologicheskikh metodov na funktsionalnoe sostoianie i endokrinnuiu reguliatsiiu gastroduodenal'noi oblasti u bol'nykh iazvennoi bolezn'iu dvenadtsatiperstnoi kishki.

A study of 102 patients with duodenal ulcers showed a salubrious clinical effect of mud therapy on a course of the disease, alkalizing duodenal function, indices of thyroid hormones, gastrin and blood cyclic nucleotides in 62.7% of cases.