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[Intestinal endotoxin in the pathogenesis of ocular inflammatory diseases and the antiendoxin constituent of its treatment].

Vyshegurov, Ia Kh; Anikhovskaia, I A; Batmanov, Iu E; Iakovlev, M Iu.

Patol Fiziol Eksp Ter ; (1): 12-4, 2007.

Article in Russian | MEDLINE | ID: mdl-17526210

ABSTRACT

Blood was studied in 119 patients with ocular inflammatory lesions: endophthalmitis (n = 10), iridocyclitis of viral (n = 47) and unknown (n = 62) genesis, by using the procedures developed by the authors to determine the integral values of the concentration of endotoxin in systemic blood flow and the activity of antiendotoxin immunity. Intestinal endotoxin aggression was found to be involved in the pathogenesis of ocular inflammatory diseases. The use of drugs and procedures, which could diminish the entry of intestinal endotoxin into the blood stream and intensify the processes of its binding and release from systemic blood circulation, substantially enhanced the efficiency of a therapeutic process.

Subject(s)

Endotoxins/blood , Eye Infections/etiology , Eye Infections/therapy , Uveitis/etiology , Adult , Aged , Endophthalmitis/blood , Endophthalmitis/etiology , Endophthalmitis/therapy , Endotoxins/toxicity , Eye Infections/blood , Gentamicins/therapeutic use , Humans , Intestinal Diseases/microbiology , Iridocyclitis/blood , Iridocyclitis/etiology , Iridocyclitis/therapy , Lipopolysaccharides/blood , Luminol/analogs & derivatives , Middle Aged , Phthalazines/therapeutic use , Treatment Outcome , Uveitis/blood , Uveitis/therapy

[Etiology of endotoxin aggression and its role as an obligate pathogenetic factor in iridocyclites of different origins].

Vyshegurov, Ia Kh; Anikhovskaia, I A; Rascheskov, A Iu; Usov, I A; Iakovlev, M Iu.

Fiziol Cheloveka ; 32(6): 109-13, 2006.

Article in Russian | MEDLINE | ID: mdl-17180900

Subject(s)

Anti-Bacterial Agents/therapeutic use , Iridocyclitis/etiology , Lipopolysaccharides/blood , Adult , Aged , Anti-Bacterial Agents/administration & dosage , Antibodies, Bacterial/immunology , Humans , Intestines/immunology , Intestines/microbiology , Iridocyclitis/blood , Iridocyclitis/prevention & control , Lipopolysaccharides/immunology , Middle Aged , Secondary Prevention

[Increased antibody titers to bifidobacteria as a marker of intestinal dysbacteriosis].

Anikhovskaia, I A; Vyshegurov, Ia Kh; Likhoded, V G; Iakovlev, M Iu.

Fiziol Cheloveka ; 31(2): 132-4, 2005.

Article in Russian | MEDLINE | ID: mdl-15889831

Subject(s)

Antibodies, Bacterial/analysis , Bacterial Infections/diagnosis , Bifidobacterium/immunology , Intestinal Diseases/diagnosis , Adult , Bacterial Infections/immunology , Bacterial Infections/microbiology , Biomarkers/analysis , Humans , Intestinal Diseases/immunology , Intestinal Diseases/microbiology , Middle Aged

[Bifidobacteria as a means of prevention or treatment of endotoxin aggression in patients with chronic diseases during remission or exacerbation]. / Bifidumbakterii kak sredstvo profilaktiki i lecheniia "éndotoksinovoi aggressii " u patsientov s khronicheskimi zabolevaniiami v stadiiakh remissii i obostreniia.

Anikhovskaia, I A; Vyshegurov, Ia Kh; Usov, I A; Iakovlev, M Iu.

Fiziol Cheloveka ; 30(6): 125-7, 2004.

Article in Russian | MEDLINE | ID: mdl-15624734

Subject(s)

Bifidobacterium , Endotoxemia/therapy , Lipopolysaccharides/blood , Probiotics/therapeutic use , Adult , Chronic Disease , Endotoxemia/blood , Endotoxemia/prevention & control , Female , Humans , Male , Middle Aged , Secondary Prevention

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