1.
Org Lett
; 11(10): 2129-32, 2009 May 21.
Article
in English
| MEDLINE
| ID: mdl-19382768
ABSTRACT
Mixing readily available alkynes, pyrroles, and triethylsilane along with an indium catalyst was found to be an efficient procedure to introduce alkyl groups onto a beta-position of pyrroles in a complete regioselective manner. This is the first demonstration of catalytic beta-alkylation of pyrroles in a single step.