ABSTRACT
Digital ulcers are a serious complication in 50% of patients with scleroderma. These ulcers have the potential to resist conventional therapies. There have been several reviews of scleroderma care over the last 5 years, but there are new developments in this field that advance clinician knowledge. This review provides an overview of previous digital ulcer management and a concise summary of new peer-reviewed literature on the topic since 2015 to provide guidance to practitioners and researchers seeking well-supported and novel/off-label therapies to consider.
Subject(s)
Fingers/pathology , Iloprost/therapeutic use , Scleroderma, Localized/diagnosis , Skin Ulcer/drug therapy , Vasodilator Agents/therapeutic use , Female , Humans , Male , Prognosis , Risk Assessment , Scleroderma, Localized/complications , Skin Ulcer/etiology , Treatment Outcome , Wound Healing/physiologyABSTRACT
Basal cell carcinoma (BCC) is the most common malignant skin cancer diagnosed in the United States. We present the case of a 67-year-old man whose knee pain and tumor of 2 years' duration was initially diagnosed as a dermoid cyst and bursitis. Dermatology referral confirmed a delayed diagnosis of BCC. This case provides insight into the range of BCC presentations and reminds clinicians to consider BCC when the differential diagnosis includes a dermoid cyst and bursitis.
Subject(s)
Bursitis/diagnosis , Carcinoma, Basal Cell/diagnosis , Dermoid Cyst/diagnosis , Skin Neoplasms/diagnosis , Aged , Carcinoma, Basal Cell/pathology , Diagnosis, Differential , Diagnostic Errors , Humans , Knee , Male , Mohs Surgery , Skin Neoplasms/pathologyABSTRACT
Trypophobia is the fear of patterns of clustered holes, bumps, or nodules. Trypophobia has a special relationship with dermatology because of its effects on individuals with skin disease, its relationship with disease avoiding behavior, and its utilization in many online skin disease hoaxes. Trypophobic patterns on skin and characters can be found in movies, TV shows, and videogames. Several popular horror villains take advantage of trypophobic patterns like Freddy Kreuger, Jason Vorhees, and Pinhead. Most recently, another blockbuster villain has joined their ranks - Killmonger. Public health messaging about these biases and the often noncontagious nature of skin disease is warranted to attenuate public stigma of skin disease perpetuated by media.
Subject(s)
Cicatrix , Motion Pictures , Phobic Disorders , Skin Diseases , Social Stigma , Television , HumansABSTRACT
The Neuroimaging Informatics Tools and Resources Clearinghouse, NITRC is a newly established Web site for organizing knowledge about the resources publicly available functional MRI and related structural imaging analysis. Based on GForge, it provides a common environment for downloading, discussion, education, rating, and documentation for a growing number of resources. Its design and current status is presented.
