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1.
Anesth Analg ; 97(5): 1303-1309, 2003 Nov.
Article in English | MEDLINE | ID: mdl-14570643

ABSTRACT

UNLABELLED: Popliteal sciatic nerve block is a commonly used technique for surgery involving the foot and ankle. However, pain can be difficult to control as the local anesthetic block wears off. Therefore, we hypothesized that extending the block by using a continuous infusion of bupivacaine (0.25%) would provide improved pain management and might facilitate the recovery process after foot or ankle surgery. In this randomized, double-blinded, placebo-controlled study, 24 consenting patients undergoing foot or ankle surgery with a standardized general anesthetic technique were studied. Before surgery, a popliteal sciatic nerve block was performed in all patients with an 18-gauge Tuohy epidural needle and a peripheral nerve stimulator. After injection of bupivacaine 0.25% 30 mL and placement of a 20-gauge catheter, patients were randomly assigned to receive either 0.9% saline (control) or bupivacaine 0.25% at a constant rate of 5 mL/h for up to 48 h after surgery. An 11-point verbal rating scale (0 = no pain to 10 = worst pain imaginable) was used to assess the severity of pain. Opioid analgesic use was recorded at specific time intervals after surgery. Follow-up evaluations were performed at 24 h, 48 h, 72 h, and 1 week after surgery to assess pain scores, as well as patient satisfaction with their pain management and quality of recovery, by using a 100-point verbal rating scale (1 = highly dissatisfied to 100 = highly satisfied). In the bupivacaine group, there was a statistically significant reduction in the maximal pain scores (>50%) and in opioid use (>60%) during the postoperative period compared with the control group. Patient satisfaction with postoperative pain management (95 +/- 3 versus 77 +/- 13) and quality of recovery (96 +/- 7 versus 83 +/- 14) was significantly improved in the bupivacaine group (versus control). In addition, 40% of the patients in the bupivacaine group (versus none in the control group) were able to be discharged home on the day of surgery (P = 0.087). In conclusion, a continuous infusion of bupivacaine 0.25% decreased postoperative pain and the need for opioid analgesic rescue medication after orthopedic surgery involving the foot and ankle, leading to improved patient satisfaction and quality of recovery. IMPLICATIONS: A continuous infusion of bupivacaine 0.25% (versus saline) at the popliteal fossa by using a simple elastomeric pump is an effective method of decreasing postoperative pain, reducing the opioid analgesic requirement, and increasing patient satisfaction with pain management after orthopedic surgery involving the foot and ankle. More importantly, the use of the continuous sciatic nerve block in the popliteal fossa facilitated an earlier discharge after lower extremity surgery.


Subject(s)
Ankle/surgery , Foot/surgery , Nerve Block , Orthopedic Procedures , Pain, Postoperative/drug therapy , Sciatic Nerve , Adolescent , Adult , Aged , Aged, 80 and over , Anesthetics, Local , Bupivacaine , Female , Follow-Up Studies , Humans , Male , Middle Aged , Nerve Block/adverse effects , Pain Measurement/drug effects , Postoperative Complications/epidemiology , Prospective Studies
2.
Anesthesiology ; 97(6): 1387-92, 2002 Dec.
Article in English | MEDLINE | ID: mdl-12459663

ABSTRACT

BACKGROUND: This study was designed to evaluate transcutaneous electrical acupoint stimulation (acustimulation) using the ReliefBand compared with ondansetron for the treatment of established postoperative nausea and vomiting (PONV) after outpatient laparoscopic surgery. METHODS: After the authors obtained institutional review board approval and written informed consent, 268 outpatients were enrolled in this randomized, double-blind, placebo- and sham-controlled study. All patients received antiemetic prophylaxis with metoclopramide, 10 mg intravenously, or droperidol, 0.625 mg intravenously, after induction of anesthesia. A total of 90 patients developed PONV in the recovery units and were randomized to one of three treatment groups: (1) the ondansetron group received 4 mg intravenous ondansetron and a sham ReliefBand; (2) the acustimulation group received 2 ml intravenous saline and a ReliefBand; and (3) the combination group received 4 mg intravenous ondansetron and a ReliefBand. A rescue antiemetic (10 mg intravenous metoclopramide) was administered only if the PONV symptoms persisted for 15 min or longer after initiating the treatment. A blinded observer recorded the recovery times, emetic symptoms, rescue antiemetics, maximum nausea scores, complete response to study treatment, and time to achieve discharge criteria. Postdischarge side effects, as well as patient satisfaction and quality of recovery scores, were assessed at 24 and 72 h after surgery. RESULTS: The combination group had a significantly higher complete response rate than the acustimulation group (73% vs.40%, P <0.01). In addition, fewer patients (8 vs. 18) in the combination (vs. acustimulation) group experienced subsequent emetic events (P < 0.03). However, there were no significant differences between the three groups with respect to patient satisfaction and quality of recovery scores. CONCLUSIONS: Acustimulation with the ReliefBand can be used as an alternative to ondansetron for the treatment of established PONV. However, the use of ondansetron (4 mg intravenously) in combination with the ReliefBand device improved the complete response rate to the acustimulation therapy.


Subject(s)
Anesthesia, General , Antiemetics/therapeutic use , Ondansetron/therapeutic use , Patient Satisfaction , Postoperative Nausea and Vomiting/drug therapy , Transcutaneous Electric Nerve Stimulation , Adult , Antiemetics/adverse effects , Double-Blind Method , Humans , Laparoscopy , Ondansetron/adverse effects , Postoperative Nausea and Vomiting/therapy
3.
Anesth Analg ; 94(2): 360-1, table of contents, 2002 Feb.
Article in English | MEDLINE | ID: mdl-11812699

ABSTRACT

IMPLICATIONS: Obese patients have successfully undergone over 650 consecutive uncomplicated ECT treatments without any special precautions at two major U.S. medical centers.


Subject(s)
Anesthesia, General , Electroconvulsive Therapy , Obesity , Adult , Aged , Anesthesia, General/adverse effects , Anesthesia, General/methods , Gastric Emptying , Humans , Middle Aged , Obesity/physiopathology , Pneumonia, Aspiration/prevention & control , Risk Factors
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