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Ovulation-inducing activity of luliberin (LHRH) complexed by copper(II), nickel(II), and zinc(II) ions.

Kozlowski, H; Masiukiewicz, E; Potargowicz, E; Rzeszotarska, B; Walczewska-Sumorok, A.

J Inorg Biochem ; 40(2): 121-5, 1990 Oct.

Article in English | MEDLINE | ID: mdl-2092076

ABSTRACT

We have shown that the complexation of luteinizing hormone releasing hormone, luliberin (LHRH), a hypothalamic neurohormone, by Cu(II), Ni(II), and Zn(II) may affect its basic, ovulation-inducing potency in the dose responsive manner. Some explanation of the obtained results are offered here.

Subject(s)

Copper , Gonadotropin-Releasing Hormone/analogs & derivatives , Nickel , Ovulation/drug effects , Zinc , Amino Acid Sequence , Animals , Female , Gonadotropin-Releasing Hormone/chemistry , Gonadotropin-Releasing Hormone/pharmacology , Molecular Sequence Data , Ovulation Induction , Rats , Rats, Inbred BUF , Rats, Inbred Strains

Ovulation-inducing activity of synthetic luliberin (LH-RH).

Jakubowska-Naziemblo, B; Walczewska-Sumorok, A; Rzeszotarska, B; Masiukiewicz, E.

Endokrynol Pol ; 37(1): 31-4, 1986.

Article in English | MEDLINE | ID: mdl-3525132

Subject(s)

Gonadotropin-Releasing Hormone/pharmacology , Ovulation Induction , Animals , Female , Hormones/pharmacology , Rats , Rats, Inbred BUF , Rats, Inbred Strains

ABSTRACT

Subject(s)

Subject(s)

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