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1.
RNA Metabolism: Modifying sex in flies.
Waldron, Denise.
Nat Rev Mol Cell Biol ; 18(2): 70-71, 2017 02.
Article in English | MEDLINE | ID: mdl-28053349

Subject(s)
Biochemical Phenomena , Drosophila/genetics , Animals , Drosophila melanogaster/genetics , RNA
2.
Gene therapy: In vivo gene editing in non-dividing cells.
Waldron, Denise.
Nat Rev Genet ; 18(1): 1, 2017 01.
Article in English | MEDLINE | ID: mdl-27916984

Subject(s)
CRISPR-Cas Systems , Gene Editing , Clustered Regularly Interspaced Short Palindromic Repeats , Genetic Therapy
3.
DNA repair: RNA-DNA hybrids: double-edged swords.
Waldron, Denise.
Nat Rev Genet ; 18(1): 3, 2017 01.
Article in English | MEDLINE | ID: mdl-27867192

Subject(s)
DNA , RNA , DNA Repair
4.
Development: Modifying sex in flies.
Waldron, Denise.
Nat Rev Genet ; 18(2): 68-69, 2017 02.
Article in English | MEDLINE | ID: mdl-28029164

Subject(s)
Drosophila , Animals
5.
Genetic variation: Diving deep into the genome.
Waldron, Denise.
Nat Rev Genet ; 17(12): 716-717, 2016 12.
Article in English | MEDLINE | ID: mdl-27773921

Subject(s)
Genetic Variation/genetics , Genome, Human/genetics , High-Throughput Nucleotide Sequencing/methods , Humans , RNA Splice Sites/genetics
6.
Genetic engineering: Allele-specific genome editing of disease loci.
Waldron, Denise.
Nat Rev Genet ; 17(11): 660, 2016 11.
Article in English | MEDLINE | ID: mdl-27694808

Subject(s)
Gene Editing , Genetic Engineering , Genetic Loci/genetics , Genome, Human/genetics , Huntington Disease/genetics , Alleles , Animals , CRISPR-Cas Systems/genetics , Humans , Mutation/genetics
7.
Mobile elements: Putting the brakes on ageing.
Waldron, Denise.
Nat Rev Genet ; 17(11): 658-659, 2016 11.
Article in English | MEDLINE | ID: mdl-27667391

Subject(s)
Aging/genetics , DNA Transposable Elements/genetics , Animals , DNA Breaks , Drosophila melanogaster/genetics , Heterochromatin/genetics , Longevity/genetics
8.
Genetic engineering: Rewriting the rules of inheritance.
Waldron, Denise.
Nat Rev Genet ; 17(10): 583, 2016 10.
Article in English | MEDLINE | ID: mdl-27528111

Subject(s)
Caenorhabditis elegans , Genetic Engineering , Animals , Databases, Genetic , Humans , Parents
9.
Chromatin: Xist as a recruitment tool.
Waldron, Denise.
Nat Rev Genet ; 17(10): 580, 2016 10.
Article in English | MEDLINE | ID: mdl-27573373

Subject(s)
Chromatin , RNA, Long Noncoding , Nuclear Lamina , X Chromosome
10.
Chromatin: Chromatin variation underLINEd.
Waldron, Denise.
Nat Rev Genet ; 17(9): 504-5, 2016 09.
Article in English | MEDLINE | ID: mdl-27452111
11.
Cancer genomics: A multi-layer omics approach to cancer.
Waldron, Denise.
Nat Rev Genet ; 17(8): 436-7, 2016 07 15.
Article in English | MEDLINE | ID: mdl-27418154

Subject(s)
Genome/genetics , Neoplasms/genetics , DNA Copy Number Variations/genetics , Genomics/methods , Humans , Metabolomics/methods , Proteomics/methods
12.
Circadian genetics: Tick Tock - keep your eyes on the clock.
Waldron, Denise.
Nat Rev Genet ; 17(8): 439, 2016 08.
Article in English | MEDLINE | ID: mdl-27346640

Subject(s)
Circadian Clocks/genetics , Animals , Gene Expression/genetics , Genes, Reporter/genetics , Humans , Luminescent Proteins/genetics , Promoter Regions, Genetic/genetics
13.
Technique: CRISP(e)R genetic mapping.
Waldron, Denise.
Nat Rev Genet ; 17(7): 375, 2016 07.
Article in English | MEDLINE | ID: mdl-27180662
14.
Human genetics: Splicing: linking genetic variation and disease.
Waldron, Denise.
Nat Rev Genet ; 17(6): 317, 2016 06.
Article in English | MEDLINE | ID: mdl-27156973
15.
Genetic screens: Finding the resilient few.
Waldron, Denise.
Nat Rev Genet ; 17(6): 316, 2016 06.
Article in English | MEDLINE | ID: mdl-27109919
16.
Small RNAs: Regulating transgenerational epigenetics.
Waldron, Denise.
Nat Rev Genet ; 17(6): 315, 2016 06.
Article in English | MEDLINE | ID: mdl-27067262
17.
Development: A colourful map of cell fate.
Waldron, Denise.
Nat Rev Genet ; 17(5): 252, 2016 May.
Article in English | MEDLINE | ID: mdl-27040485

Subject(s)
DNA Barcoding, Taxonomic/methods , Zebrafish/genetics , Zebrafish/physiology , Animals
18.
Genetic testing: Clinical sequencing right on target.
Waldron, Denise.
Nat Rev Genet ; 17(5): 253, 2016 May.
Article in English | MEDLINE | ID: mdl-26996078

Subject(s)
Genetic Testing , Sequence Analysis, DNA , High-Throughput Nucleotide Sequencing , Humans
19.
Microbial genetics: CRISPR memories of RNA.
Waldron, Denise.
Nat Rev Genet ; 17(4): 192-3, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26948816

Subject(s)
Bacterial Proteins/metabolism , CRISPR-Associated Proteins/metabolism , CRISPR-Cas Systems , Clustered Regularly Interspaced Short Palindromic Repeats , Marinomonas/enzymology , Mutant Chimeric Proteins/metabolism , RNA-Directed DNA Polymerase/metabolism , RNA/metabolism
20.
Epigenetics: A three-state model for epigenetic silencing.
Waldron, Denise.
Nat Rev Genet ; 17(4): 192-3, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26900023

Subject(s)
Chromatin/metabolism , DNA Methylation , Gene Silencing , Histones/metabolism , Animals , Humans
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