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6.
Ann Pediatr Cardiol ; 15(5-6): 447-452, 2022.
Article in English | MEDLINE | ID: mdl-37152511

ABSTRACT

Background: The increase in the survival of patients with D-Transposition of the great arteries (TGA) after arterial switch operation (ASO) has now turned our focus to the evaluation of mid and long-term outcomes. Although most patients are followed by conventional echocardiography, the study of cardiac functionality and morphometric parameters in children with TGA after ASO is scarce. The present study aims to describe the functional and morphometric echocardiographic changes in children after ASO. Methods: We performed an observational study in patients aged 1-5 years with TGA who underwent neonatal ASO. Morphometric and functional echocardiographic parameters were analyzed in 21 patients and compared with 52 age-matched healthy controls. Results: We found morphological and functional changes, especially in the right ventricle, which is more globular (right ventricle [RV] basal sphericity index 1.5 vs. 1.8, P = 0.016), and with a decreased systolic function compared to healthy controls (fractional area change 51 vs. 58%, P = 0.006; tricuspid annular plane systolic excursion 13 vs. 20 mm, P = 0.001; s' 7 vs. 12 cm/s, P = 0.001). In the speckle-tracking strain imaging, there was a decrease in the longitudinal deformation of the apical septal myocardium (-23% vs. -27%; P = 0.005). Preoperative systemic overload to the right ventricle could be an important factor in the origin of these changes. Conclusions: In patients with TGA after ASO, there are morphometric and functional echocardiographic changes, such as globular form and decreased function, especially in the RV; the effect of these changes on long-term outcomes would require prospective follow-up studies.

8.
Cardiol Young ; 30(7): 919-922, 2020 Jul.
Article in English | MEDLINE | ID: mdl-32498738

ABSTRACT

Idiopathic dilatation of the right atrium is an isolated enlargement of the right atrium in the absence of other cardiac lesions. This rare anomaly has a clinical spectrum ranging from asymptomatic to heart failure or even sudden death. It can be associated with atrial arrhythmias and thrombus formation. Antiplatelet therapy is prescribed in most cases reported in the literature, and reduction plasty is indicated when there is rapid growth of the right atrium, compression of adjacent structures, or refractory arrhythmias. We report four cases of idiopathic dilatation of the right atrium diagnosed during prenatal screening. We describe the intrauterine course and management in postnatal life until early childhood.


Subject(s)
Aneurysm , Heart Atria , Arrhythmias, Cardiac , Child, Preschool , Dilatation , Dilatation, Pathologic , Female , Heart Atria/diagnostic imaging , Humans , Pregnancy
9.
Pediatr Cardiol ; 41(4): 687-694, 2020 Apr.
Article in English | MEDLINE | ID: mdl-31919591

ABSTRACT

To improve the understanding of the pathophysiology of transposition of the great arteries with intact ventricular septum (TGA/IVS) and the cardiac remodeling occurring from fetal to neonatal life, we performed a morphometric and functional echocardiographic assessment in fetuses and newborns. This was a prospective case-control study performed in a tertiary referral center, which included fetuses and newborns with a diagnosis of TGA/IVS between 2011 and 2018. Morphometry and systolic and diastolic function parameters were compared with age and body surface-matched healthy controls. Twenty-one TGA/IVS patients were included during the study period and morphometric and functional echocardiographic data were recorded. TGA/IVS patients showed morphometric and functional changes of increased overall volume and output, predominantly in the aortic component from fetus to newborn, probably due to compensatory mechanisms secondary to brain hypoxia.


Subject(s)
Echocardiography/methods , Transposition of Great Vessels/diagnostic imaging , Ventricular Septum/diagnostic imaging , Case-Control Studies , Female , Fetal Heart/diagnostic imaging , Gestational Age , Humans , Infant, Newborn , Male , Prospective Studies , Transposition of Great Vessels/physiopathology
10.
World J Pediatr Congenit Heart Surg ; 10(5): 651-653, 2019 09.
Article in English | MEDLINE | ID: mdl-31496401

ABSTRACT

Obstructive total anomalous pulmonary venous return (TAPVR) is a potentially life-threatening clinical condition and a surgical emergency. Left-sided partial anomalous pulmonary venous return (PAPVR) in association with a subdivided left atrium, also known as cor triatriatum sinister (CTS), is a very rare malformation that can mimic obstructive TAPVR. We present a case of a newborn with clinical manifestation of cardiogenic shock caused by CTS and PAPVR.


Subject(s)
Cor Triatriatum/surgery , Scimitar Syndrome/surgery , Shock, Cardiogenic/surgery , Cor Triatriatum/complications , Heart Atria/surgery , Heart Defects, Congenital/complications , Heart Defects, Congenital/surgery , Humans , Infant, Newborn , Male , Pulmonary Veins/abnormalities , Pulmonary Veins/surgery , Scimitar Syndrome/complications , Shock, Cardiogenic/complications
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