ABSTRACT
The authors report on a series of 324 patients operated on for cholelithiasis. They summarize the histological findings obtained by detailed examination of the surgical specimens carried out by one pathologist. The relatively high rate (43%) of severe pathological changes in the gallbladder wall in emphasized as these may be sites of predilection for the development of carcinoma. Three cases of only histologically established carcinoma are briefly described. In two of them carcinoma developed on the basis of chronic fibroproductive cholecystitis. In the third case the gall bladder was not removed and thus histologically not examined. In the light of their findings, the authors strongly advocate early cholecystectomy, particularly in patients of advanced age groups.
Subject(s)
Cholecystectomy , Cholelithiasis/surgery , Gallbladder Neoplasms/prevention & control , Adult , Aged , Cholecystitis/complications , Cholelithiasis/complications , Female , Gallbladder Neoplasms/etiology , Gallbladder Neoplasms/pathology , Humans , Male , Middle Aged , Time FactorsSubject(s)
Postoperative Complications/epidemiology , Pulmonary Embolism/epidemiology , Adolescent , Adult , Aged , Child , Humans , Middle Aged , Pulmonary Embolism/etiologySubject(s)
Colonic Neoplasms/diagnosis , Colonoscopy , Intestinal Polyps/surgery , Aged , Humans , Intestinal Polyps/diagnosis , Intraoperative Period , MaleABSTRACT
During the period 1959 to 1968, a total of 158 patients with carcinoma of the rectum were treated at the surgical department of the Oncological Institute in Bratislava. All these patients were retro spectively classified according to the TNM system into four clinical stages as follows: Stage I -- 26 (16.46%). Stage II -- 12 (7.59%), Stage III -- 61 (36.61%) and Stage IV -- 59 (53.39%) of the patient. Surgical treatment was supplemented with irradiation in 85 (53.73%) of the patients with chemotherapy in 15 (9.49%). All the findings were verified histologically. Favorable results as regards the 5-year survival rate in accordance with literature data were achieved in the early stages of the affection, while in advanced stages this survival rate was rather low, the majority of the patients died in the first and second year following initiation of treatment. The authors express the view that in future, oncologists will have to devote more attention to an early diagnosis and treatment of precanceroses, and this not solely in patients with a carcinoma of the rectum, but also in its other localizations.
