ABSTRACT
The dynamics of blood lead (Pb-B) and blood zinc protoporphyrin (ZPP-B) of women in early pregnancy and parturient women with lead exposure and the effects on fetus development were investigated. Pb-B of lead-exposed women was high: 0.984 mumol/L (20.38 micrograms/dl) and ZPP was 84.52 micrograms/dl. Cord blood Pb-B was 0.896 mumol/L (18.56 micrograms/dl) and cord blood ZPP was 69.24 micrograms/dl. In the control group, Pb-B was 0.261 mumol/L (5.41 micrograms/dl), ZPP-B, 37.59 micrograms/dl, cord blood, Pb-B 0.34 mumol/L (7.03 micrograms/dl), and cord ZPP-B 49.0 micrograms/dl. There was a significant correlation between blood lead and blood ZPP, maternal Pb-B and cord Pb-B, maternal Pb-B and cord ZPP-B. The significance of the consistency of high level Pb-B and the effects on fetus development is discussed.
Subject(s)
Fetal Blood/chemistry , Lead/blood , Occupational Exposure , Pregnancy/blood , Protoporphyrins/blood , Adult , China , Embryonic and Fetal Development , Female , Fetal Death/etiology , Humans , Lead/adverse effects , Linear Models , Obstetric Labor, Premature/etiologyABSTRACT
This paper presents a study of five metals content in biosamples of placenta, maternal venous blood, cord blood from 32 occupationally lead exposed female workers and 32 controls. The results showed that lead levels in biosamples of lead exposed individuals were significantly greater than those from controls. Results also showed that there existed very close relationships between placental lead and maternal blood lead, placental lead and cord blood lead, maternal blood lead and cord blood lead, showing that there was a lead transfer from the mother to the child via the placenta. The relationships between metals in the biosamples were also discussed in the paper.
