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3.
Insights Imaging ; 8(3): 365-376, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28303554

ABSTRACT

Non-malignant oesophageal diseases are critical to recognize, but can be easily overlooked or misdiagnosed radiologically. In this paper, we cover the salient clinical features and imaging findings of non-malignant pathology of the oesophagus. We organize the many non-malignant diseases of the oesophagus into two major categories: luminal disorders and wall disorders. Luminal disorders include dilatation/narrowing (e.g. achalasia, scleroderma, and stricture) and foreign body impaction. Wall disorders include wall thickening (e.g. oesophagitis, benign neoplasms, oesophageal varices, and intramural hematoma), wall thinning/outpouching (e.g. epiphrenic diverticulum, Zenker diverticulum, and Killian-Jamieson diverticulum), wall rupture (e.g. iatrogenic perforation, Boerhaave Syndrome, and Mallory-Weiss Syndrome), and fistula formation (e.g. pericardioesophageal fistula, tracheoesophageal fistula, and aortoesophageal fistula). It is the role of the radiologist to recognize the classic imaging patterns of these non-malignant oesophageal diseases to facilitate the delivery of appropriate and prompt medical treatment. TEACHING POINTS: • Nonmalignant oesophageal disease can be categorised by the imaging appearance of wall and lumen. • Scleroderma and achalasia both cause lumen dilatation via different pathophysiologic pathways. • Oesophageal wall thickening can be inflammatory, neoplastic, traumatic, or vascular in aetiology.

4.
Insights Imaging ; 7(3): 431-48, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27085884

ABSTRACT

The large airways can be affected by a wide spectrum of acquired benign and malignant diseases. These lesions may present as focal or diffuse processes and with narrowing or widening of the airway. Some of these may be asymptomatic for quite some time and may be incidentally detected on imaging, while others may be symptomatic, causing airway compromise. There may be a characteristic radiograph and computed tomography (CT) appearance, suggesting a narrow differential. When the imaging findings are not definitive, tissue may be obtained for pathological analysis. It behooves the radiologist to be familiar with the pathologic findings that correlate with the radiographic or CT appearance of the most frequently seen large airway lesions. In this way, we may improve our diagnostic accuracy. This paper will present the imaging findings of the most prevalent tracheobronchial lesions along with any associated pathology. Teaching Points • The large airways can be affected by many acquired benign and malignant diseases.• Large airway lesions may present as focal or diffuse processes, with narrowing or widening.• There may or may not be characteristic imaging appearance of large airway disease.• If imaging findings are not definitive, tissue may be obtained for pathological analysis.

5.
Insights Imaging ; 5(4): 493-506, 2014 Aug.
Article in English | MEDLINE | ID: mdl-25001069

ABSTRACT

BACKGROUND: Pulmonary arteries are not just affected by thrombus. Congenital and acquired conditions can also involve the pulmonary arteries. An awareness of these conditions is important for the radiologist interpreting chest computed tomography (CT). METHODS: The anatomy of the pulmonary arteries was reviewed. CT and magnetic resonance (MR) acquisition protocols for imaging the pulmonary arteries were discussed. The imaging appearances of congenital and acquired anomalies involving the pulmonary arteries, using CT and other modalities, were presented. RESULTS: Imaging features of congenital anomalies presented include pulmonary agenesis, partial pulmonary artery agenesis, patent ductus arteriosus, pulmonary artery sling, congenital pulmonary artery stenosis and coronary to pulmonary artery fistula. Acquired pulmonary artery anomalies discussed include arteritis, infected aneurysm and sarcoma. Pulmonary artery filling defects besides thromboembolism are also discussed, including foreign body emboli. Imaging features of bronchogenic carcinoma and mediastinal fibrosis demonstrating compression of the pulmonary arteries are presented, followed by a brief discussion of post repair appearance of the pulmonary arteries for congenital heart disease. CONCLUSIONS: Congenital and acquired pulmonary artery anomalies have a characteristic appearance on a variety of imaging modalities. An acquaintance with the imaging features of these anomalies is needed to avoid misinterpretation and reach the correct diagnosis. Teaching Points • Discuss a variety of congenital and acquired anomalies of the pulmonary arteries. • Discuss the imaging appearance of the presented congenital or acquired pulmonary artery anomalies. • Describe CT and MR acquisition protocols for imaging the pulmonary arteries. • Review the anatomy of the pulmonary arteries.

6.
Appl Immunohistochem Mol Morphol ; 17(5): 451-7, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19349855

ABSTRACT

Malignant solitary fibrous tumor (MSFT) is a rare neoplasm. Three cases of MSFT with unusual features, including 1 pleural and 2 extrapleural, are reported. A 64-year-old woman with a large right thoracic MSFT and episodes of severe hypoglycemia experienced resolution of her hypoglycemia immediately after resection of the MSFT. A 27-year-old woman with primary retroperitoneal MSFT had pulmonary metastases 10 months after resection of the primary tumor. A 54-year-old man with an intracranial solitary fibrous tumor suffered from multiple pulmonary metastases and local recurrence 21 and 28 months after resection of the primary tumor, respectively. All 3 cases of solitary fibrous tumor displayed malignant features. The tumor cells in each case were positive for CD34 and Bcl-2, but negative for cytokeratin, smooth muscle actin, S-100, and c-kit. In addition, the tumor cells in the case with concomitant hypoglycemia were strongly positive for insulin-like growth factor-II. The histopathologic diagnostic criteria for MSFT, the differential diagnosis with other spindle cell tumors, and the mechanism of MSFT-derived hypoglycemia via insulin-like growth factor-II are discussed.


Subject(s)
Fibroma/diagnosis , Adult , Female , Fibroma/diagnostic imaging , Fibroma/metabolism , Fibroma/pathology , Humans , Immunohistochemistry , Male , Middle Aged , Tomography, X-Ray Computed
7.
Pathology ; 41(3): 234-41, 2009.
Article in English | MEDLINE | ID: mdl-19291535

ABSTRACT

AIMS: Uncommon cases of lung metastasis from different types of uterine neoplasms with a long tumour-free interval after hysterectomy are reported. METHODS AND RESULTS: Four cases were retrieved from our surgical pathology archives. Case 1 was a 68-year-old woman who had three pulmonary nodules 23 years after hysterectomy for low-grade endometrial stromal sarcoma (LGESS). The nodules obtained with video-assisted thoracic surgeries were consistent with metastatic LGESS. Case 2 was a 36-year-old woman who had numerous bilateral pulmonary nodules 6 years after hysterectomy for leiomyoma. A transthoracic biopsy revealed benign metastasising leiomyoma. Case 3 was a 77-year-old woman who had a large lung mass with satellite nodules 17 years after hysterectomy with bilateral salpingo-oophorectomy and subsequent radiotherapy for endometrial endometrioid adenocarcinoma (EEA). The biopsied and resected lung tumour was consistent with metastatic EEA. Case 4 was a 51-year-old woman who underwent total hysterectomy and subsequent radiotherapy for endocervical adenocarcinoma 12 years ago and lung lobectomy for metastatic disease 8 years ago. She then developed two pulmonary lesions 14 months ago, and these resected after radiotherapy were metastatic endocervical adenocarcinoma. CONCLUSIONS: A review of the literature revealed that late pulmonary metastasis from uterine neoplasms is rare but not negligible. Immunohistochemical studies and molecular tests, together with detailed clinical information and imaging findings, are important for rendering a diagnosis.


Subject(s)
Carcinoma, Endometrioid/secondary , Leiomyoma/pathology , Lung Neoplasms/secondary , Sarcoma, Endometrial Stromal/secondary , Uterine Neoplasms/pathology , Adult , Aged , Carcinoma, Endometrioid/metabolism , Female , Humans , Immunohistochemistry , Leiomyoma/metabolism , Lung Neoplasms/metabolism , Middle Aged , Sarcoma, Endometrial Stromal/metabolism , Tomography, X-Ray Computed , Uterine Neoplasms/metabolism
8.
Emerg Radiol ; 16(5): 407-9, 2009 Sep.
Article in English | MEDLINE | ID: mdl-18696131

ABSTRACT

Fat embolism is a common complication of pelvic and long bone fractures. Macroscopic fat emboli in the pulmonary arteries on computed tomography have been reported postoperatively after fixation of long bone fractures for trauma, however the quantification of attenuation values of fat emboli have been infrequently reported in the literature. We present a case of pulmonary fat embolism in a 52-year-old female after acute bony trauma sustained during a motor vehicle accident. To the authors' knowledge however, pulmonary fat embolism has not been described on the initial trauma CT scan.


Subject(s)
Embolism, Fat/complications , Fractures, Bone/diagnostic imaging , Pelvis/injuries , Pulmonary Embolism/complications , Tibia/injuries , Accidents, Traffic , Female , Fractures, Bone/complications , Humans , Middle Aged , Tomography, X-Ray Computed
9.
AJR Am J Roentgenol ; 181(4): 1101-8, 2003 Oct.
Article in English | MEDLINE | ID: mdl-14500240

ABSTRACT

OBJECTIVE: The aim of this study was to assess the prevalence and appearance of the pericardial sinuses and recesses on thin-section (2.5- or 3-mm) CT scans compared with thick-section (5- or 7-mm) CT scans. MATERIALS AND METHODS: Nine hundred forty-one consecutive contrast-enhanced chest CT scans were retrospectively evaluated. Three hundred sixty-five patients underwent thin-section CT, and 576 patients underwent thick-section CT. The prevalence and appearance of every pericardial recess were determined. RESULTS: Large recesses such as the superior aortic recess were depicted in 12.5-30.4% of patients using thick-section CT, whereas smaller recesses such as the postcaval recess were depicted in fewer than 5% of patients. With thin-section CT, the depiction rates increased significantly compared with thick-section CT (p < 0.01). Large recesses were depicted in 28.7-44.7% of patients, and smaller recesses were recognized in 10.8-19.8% of patients. Generally, most recesses were linear if they were small and became band-shaped as the fluid increased. However, the recesses were often visualized as crescent, triangle, spindle, ovoid, hemisphere, or irregular shapes. CONCLUSION: Pericardial sinuses and recesses are more frequently and better depicted on thin-section CT scans. Knowledge of their locations and shapes is helpful for distinguishing pericardial fluid from abnormal findings such as lymphadenopathy and cystic lesions.


Subject(s)
Pericardium/diagnostic imaging , Tomography, X-Ray Computed/methods , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Retrospective Studies
11.
Radiology ; 222(1): 245-51, 2002 Jan.
Article in English | MEDLINE | ID: mdl-11756733

ABSTRACT

PURPOSE: To assess frequency and significance of enlarged nonpalpable supraclavicular lymph nodes by using chest computed tomography (CT) and supraclavicular ultrasonography (US) in patients at initial diagnosis of lung cancer. MATERIALS AND METHODS: Fifty-five patients with no prior malignancy who presented with suspected and subsequently proven lung cancer of any stage or a proven but potentially resectable lung cancer were prospectively selected after chest CT. Chest CT and other radiologic findings were reviewed and tabulated. Standardized US technique was used to identify and guide needle biopsy of enlarged supraclavicular lymph nodes (> or =0.5 cm short axis). RESULTS: Twenty-two (40%) of 55 patients had supraclavicular abnormalities detected at CT and/or US. In 18 (82%) of the 22 patients, supraclavicular abnormalities were recognizable at CT. Seventeen of 22 patients had malignant nodes, and five patients had benign nodes (n = 3), a cyst (n = 1), or an indeterminate lesion (n = 1) at US-guided supraclavicular needle sampling. There were no complications. Supraclavicular metastases (31% of patients) were about as common as the combined number of patients with indeterminate (n = 13) and probably or proven malignant (n = 6) adrenal nodules (35% of patients). Supraclavicular metastases were often associated with mediastinal adenopathy or suspected extrapulmonary nonnodal metastases (P <.05). CONCLUSION: In many patients with lung cancer, chest CT that includes the neck base followed by US-guided sampling of enlarged supraclavicular lymph nodes is a simple and safe method for simultaneously establishing a tissue diagnosis and tumor nonresectability.


Subject(s)
Lung Neoplasms/pathology , Lymph Nodes/diagnostic imaging , Tomography, X-Ray Computed , Adult , Aged , Aged, 80 and over , Clavicle , Female , Humans , Lymphatic Metastasis , Male , Middle Aged , Prospective Studies , Sensitivity and Specificity , Statistics, Nonparametric , Ultrasonography
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