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1.
J Dent Sci ; 18(4): 1706-1715, 2023 Oct.
Article in English | MEDLINE | ID: mdl-37799887

ABSTRACT

Background/purpose: Intraoral repair usually takes the convenience of the patient's daily life as the starting point, taking into account the bonding strength, operational feasibility, and safety. This study aimed to evaluate the survival of composite resin by simulating cavity fracture repair in porcelain-fused-to-metal (PFM) crowns and referring to the G.V. Black classification of caries as ceramic- and metal-site exposure. Materials and methods: Mechanical sandblast experimental and a nonsandblast control groups comprised 120 samples, and interfacial locking was enhanced through acid etching, bonding, and light-curing composite resin restoration. Classes of VI buccal (B), III mesial (M), and IV mesiobuccal (MB) types, were investigated. Load tests were performed on two sets, with one set at room temperature for 24 h and the other via thermal cycling at 5 °C/50 °C 720 times. Loading was gradually applied to the samples until a maximum of 450 N was reached. Results: Results showed that 24 h survival rates of B-, M - , and MB-repaired PFM crowns were 88%, 84%, and 88%, respectively. The repaired PFM survival rates for B, M, and MB were 52%, 44%, and 28%, respectively, after thermal cycling and loading tests. Multiple logistic regression and chi-square test (α = 0.05) showed that the regression results of factors affecting survival assessment were only significant between groups after thermal fatigue (P < 0.05). Survival rate of repairing metal-site in the MB model was significantly higher than that of ceramic-sites repairing in non-blasted samples. For the MB cavity model, sandblasting can significantly improve the survival rate of the repair of ceramic parts in the MB model (P < 0.05). Conclusion: Our results suggest that sandblasting can be further considered, especially for MB cavity fractures when ceramic-site restorations are required.

2.
J Dent Sci ; 18(3): 1272-1279, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37404618

ABSTRACT

Background/purpose: Implant stability is crucial for successful osseointegration. Marginal bone level is considered an important indicator of long-term implant success and stability. The purposes of this study were to investigate 1) the effect of age, gender, bone density, implant length, and implant diameter on insertion torque (IT), primary implant stability quotient (ISQ), and secondary ISQ, 2) the impact of age, gender, bone density, implant length, implant diameter, IT, and ISQ on marginal bone loss (MBL). Materials and methods: Ninety patients who needed implant therapy were enrolled and overall 156 implants were installed to support single crowns. IT and ISQ were recorded for all implants during surgery and ISQ measurements were performed at follow-up visits. Age, gender, bone density, implant length and diameter were also registered. Radiographic evaluation of MBL was performed postoperative immediate (baseline), 3, 6, 9, 12, 18, and 24 months using digital periapical radiographs. Results: Age had little effect on IT and primary ISQ (P > 0.05). Generally, males had higher IT and primary ISQ, but no significant differences between genders were detected. Bone density showed significant effects on IT and primary ISQ. Correlation analysis revealed high positive correlations between IT/bone density and primary ISQ/implant diameter. Significant impacts of bone density and IT on MBL were found. Conclusion: Implant diameter had a more profound impact than length on IT/primary ISQ. Bone density played a considerable role in IT/primary ISQ determination. Bone density and IT had more impacts than primary ISQ on MBL.

3.
J Dent Sci ; 18(2): 730-738, 2023 Apr.
Article in English | MEDLINE | ID: mdl-37021221

ABSTRACT

Background/purpose: Palladium-silver (Pd-Ag) alloys are important as an alternative to gold-based alloys. The purpose of this study was to investigate the effect of an argon-arc vacuum pressure casting process on the recasting of the Pd-Ag alloy. Materials and methods: The recasting Pd-Ag alloys were compared with conventional horizontal centrifugal (HC) casting to an argon (Ar)-arc vacuum pressure (Ar-arc/VP) casting. The first-generation castings were made from a Pd-Ag alloy purchased from a supplier. Next-generation castings were made from 50 wt% Pd-Ag alloy before casting and 50 wt% from previous castings. This sequence was repeated over three generations to form the 2nd, 3rd and 4th recasting ingots. The ingots were then measured for marginal accuracy, interfacial oxidation, hardness and phase identification. Results: The recasting success rate of recastibility reached 100%. Compared with the HC group, the Ar-arc/VP group had better edge precision, smaller oxide layer thickness and lower hardness. The comparison of X-ray diffraction intensity showed that the relative intensities of Pd and Ag in the first, second and third generations recasting of the Ar-arc/VP group were significantly higher than those of the HC group. Phase analysis showed that the trace elements of indium and tin contents in the Pd-Ag recasting ingots of the Ar-arc/VP group were higher than those of the HC group. Conclusion: The results showed that the casting process used for recasting affected the quality of the Pd-Ag alloy. Therefore, Ar-arc/VP casting process could improve the effect of Pd-Ag recasting and maintain the alloy properties in comparison with HC casting.

4.
J Dent Sci ; 17(3): 1307-1313, 2022 Jul.
Article in English | MEDLINE | ID: mdl-35784132

ABSTRACT

Background/purpose: Cone beam computed tomography (CBCT) is frequently used in dental diagnosis and treatment. Comparative studies of the effects of CBCT on implant navigation, however, are still limited. The objective of this study was to evaluate whether the computed tomography images of the four commercial brands will affect the accuracy of the new version of IRIS implant navigation system. Materials and methods: In the first part, the accuracy of the IRIS implant navigation system was evaluated by a precision confirmation jig whose position is confirmed. In the second part, the IRIS implant navigation system was used in conjunction with 4 brands of CBCT scans analyzed by its effect on accuracy. Results: The results showed that the mean deviation of the new version of IRIS-100 system accuracy was less than 1 mm. Among the four groups, the overall average deviation caused by CBCT images showed that the 3D eXam group had the smallest error of approximately 0.94 ± 0.12 mm and the AZ 3000 CT group had the largest error of approximately 1.34 ± 0.10 mm. Conclusion: Based on the study, the accuracy of the IRIS implant navigation system will vary with the CBCT image resolution and the status of the CBCT machine.

5.
J Dent Sci ; 17(2): 1030-1034, 2022 Apr.
Article in English | MEDLINE | ID: mdl-35756796

ABSTRACT

Background/purpose: Bioceramic tetracalcium phosphate (TTCP) is used as a surface modifier on the implant surface and the clinical studies on this surface modification are still limited. The objective of this clinical study was to investigate short-term implant stability of titanium implant surfaces being modified through sandblasting and acid etching (SLA), followed by TTCP sintered bioceramic anchoring. Materials and methods: A total of 20 patients who had single tooth space were included in this study. Surface modification by SLA plus with TTCP on Ti implants with a diameter of 4.0 mm and lengths of 10 and 11.5 mm were placed. Implant stability quotient (ISQ) value was measured immediately (ISQ0) and one month (ISQ1), two months (ISQ2), three months (ISQ3), and four months (ISQ4) after implantation. Subgroup analysis was defined to location (maxilla, mandible) and bone density (soft or hard bone). Statistical analysis was performed using Friedman test and Mann-Whitney U test. Results: The mean ISQ values with standard deviation at the different time points of ISQ0 to ISQ4 were 60.03 ± 14.12, 53.48 ± 15.24, 58.91 ± 14.43, 63.14 ± 12.22, and 63.50 ± 13.61, respectively. The results showed significant differences between the ISQ1 and ISQ3 groups and between the ISQ1 and ISQ4 groups. On the other hand, there was no statistical differences between the maxilla and mandible as well as between soft and hard bone types in all implant groups. Conclusion: TTCP/titanium implant showed favorable stability in short-term ISQ values over 4 months. The locations and bone types demonstrated no effect on implant stability.

6.
Polymers (Basel) ; 14(3)2022 Jan 27.
Article in English | MEDLINE | ID: mdl-35160495

ABSTRACT

This study evaluated the in vitro characterizations of biodegradable hydrogel beads with calcium phosphate bone cement (CPC). Commercial fast-setting CPC and hydrogel beads were compared with 25%-volume hydrogel in CPC (C/0.25) in vivo. The histological behaviors and absorption rates of CPC only, hydrogel beads, and hydrogel/CPC composite were measured and compared at 4, 8, and 12 weeks. The results indicated that the C/0.25 composite can be molded and does not disintegrate when immersed in the solution, but this delays the phase transition of the CPC into the product in the early reaction process. The osteoprogenitor D1 cell affinity of the C/0.25 composite was equally competitive with that of the CPC-only. Adding hydrogel beads to CPC did not inhibit cell proliferation as well as differentiation of osteoprogenitor cells. In vivo histological evaluations did not indicate any significant difference in the CPC-only, hydrogel-only, and C/0.25 composite after 4 weeks of implantation; however, significantly less residue was observed in the C/0.25 composite relative to the CPC-only after 8 weeks. After 12 weeks of hydrogel beads implantation, the hydrogel degraded substantially, creating vacancies that were subsequently occupied by a large amount of soft tissue. New bone was formed in large quantities in the C/0.25; therefore, the C/0.25 composite is a promising option for a wide range of dental, craniofacial, and orthopedic applications.

7.
J Dent Sci ; 16(4): 1247-1254, 2021 Oct.
Article in English | MEDLINE | ID: mdl-34484593

ABSTRACT

BACKGROUND/PURPOSE: Among the ceramic materials used for all-ceramic crowns, zirconia has high biocompatibility and favorable mechanical properties, but its main drawbacks include low translucency and stress-induced phase transformation. To stabilize high-strength tetragonal zirconia polycrystal (TZP), 3-5 mol% yttria is usually added to prepare yttria-stabilized TZP (Y-TZP). In this study, the optical properties of three commercial Y-TZP ceramics were compared with those of the clinically available glass-ceramic material of lithium disilicate, and the relationship between translucency and crystal properties was analyzed in vitro. MATERIALS AND METHODS: Twelve 5-mm-thick standardized disks were prepared from three Y-TZP ceramics and one lithium disilicate block. Absolute translucency was measured using a spectrophotometer with an integrating sphere. X-ray diffraction was used to quantify the main structural parameters (i.e., preferred plane, quantitative phase, and grain size) of Y-TZP crystals. RESULTS: The product-dominated phase of Y-TZP exhibited a tetragonal lattice pattern, and the preferred planes had minor variations. The diffraction patterns of the three Y-TZP ceramics demonstrated minor effects on translucency, without significant differences (p > 0.05). The grain size of 54-70 nm was negatively related to translucency in Y-TZP. Lithium disilicate specimens had significantly higher translucency than the three Y-TZP specimens (p < 0.001). CONCLUSION: Grain size reduction played an essential role in developing highly translucent Y-TZP ceramics. The three Y-TZP ceramics were essentially opaque but exhibited poorer translucency than lithium disilicate in terms of esthetics.

8.
Polymers (Basel) ; 13(6)2021 Mar 18.
Article in English | MEDLINE | ID: mdl-33803715

ABSTRACT

Devices and medicines used in the medical field must be sterile. Gamma (γ)-irradiation is commonly used for sterilization because its high rate of penetration ensures uniform sterilization. To confirm that hydrogel macrosphere carriers inherit excellent liquid absorption with no cytotoxicity after γ-irradiation sterilization, investigating whether the physiochemical properties of hydrogel macrospheres differ before and after sterilization is essential. The present study evaluated the influence of the recommended 25-kGy γ-irradiation dose on the physicochemical characteristics and in vitro release of bovine serum albumin and vancomycin (an antibiotic medication) from alginate/gelatin with a w/w ratio of 1/4 crosslinking gel macrospheres. Gel macrosphere properties before and after sterilization were compared according to optical and scanning electron microscopy, infrared spectroscopy analysis, the amino residual crosslinking index, water absorption, degradation, sterility assurance, in vitro drug release, antibacterial ability, and cytotoxicity. The crosslinking index was almost unchanged; however, the γ-irradiation caused in situ hydrogel debonding and recrosslinking, which led to a decrease in the water absorption and increase in the degradation rate of the macrospheres after immersion. The release of gel macrospheres carrying vancomycin did not significantly affect antibacterial ability or biocompatibility after γ-irradiation. Accordingly, we conclude that γ-irradiation is suitable for macrospherical formulation.

9.
Kaohsiung J Med Sci ; 36(5): 305-310, 2020 May.
Article in English | MEDLINE | ID: mdl-32052598

ABSTRACT

Platelet concentrates have emerged as innovative autologous blood products that enhance tissue healing and regeneration in regenerative therapy. A common feature of these products is their higher than baseline platelet concentration, which improves wound healing and tissue repair. Four main categories of products can be easily defined, based on their leukocyte content and fibrin architecture: pure platelet-rich plasma, such as Cell Separator PRP or Anitua' PRGF; leukocyte- and platelet-rich plasma (L-PRP), such as PCCS or Ace PRP; pure platelet-rich fibrin (P-PRF), such as Fibrinet PRFM; and leukocyte- and platelet-rich fibrin (L-PRF), such as Choukroun's PRF. Two families contain significant concentrations of leukocytes: L-PRP and L-PRF. These four families of products have different biological signatures and mechanisms and obviously different clinical applications. An L-PRF membrane releases growth factors and matrix proteins over a period longer than 7 days, whereas a PRP gel matrix releases and disperses its growth factors in a relatively quick download. In the near future, simple and inexpensive products such as L-PRF are expected to have applications in oral-maxillofacial surgery, periodontal surgery, plastic surgery, orthopedic surgery, and sports medicine. Leukocytes substantially affect the intrinsic biology and properties of platelet concentrates, not only because they enhance immune function and antibacterial potential, but also because they have essential roles in the wound healing process. Unfortunately, their impact has been almost completely neglected in the literature. Improved understanding of the effects of leukocytes in wound healing is essential for development of new clinical applications of platelet concentrates.


Subject(s)
Blood Platelets/metabolism , Maxilla/physiology , Regenerative Medicine , Face/physiology , Humans , Leukocytes/metabolism , Platelet-Rich Plasma , Transplantation, Autologous
10.
Kaohsiung J Med Sci ; 36(3): 212-219, 2020 Mar.
Article in English | MEDLINE | ID: mdl-31785063

ABSTRACT

An in vitro investigation was performed to evaluate the bonding characteristics of porcelain fused to metal (PFM)/commercially pure titanium (cp Ti, grade II) in three firing atmospheres of under vacuum and using two noble gases argon (Ar) and helium (He). Three groups of porcelain veneers firing under vacuum, Ar, and He were prepared to evaluate the bonding of porcelain fused to the cold-rolled cp Ti. The bond strength of PFM durability by a three-point bending test, phases, microhardness of cp Ti after firing processes, and fractures were measured and evaluated. Results show the microhardness of cp Ti in group of porcelain firing under He atmosphere was significantly lower than that of the two other groups, which were in vacuum and Ar (P < .05). X-ray diffraction showed the He group produced in relatively small amounts of TiO2 and TiO oxides than other groups but featured relatively high quantity of airhole defects in the porcelain body leading to the lowest bond strength. The Ar group presented the highest bond strength of comparing with the groups under vacuum and using He (P < .05). Although the firing processes in He could efficiently prevent the diffusion of oxygen into Ti, the porcelain-cp Ti bond strength using Ar protective atmosphere presented the advantage to achieve clinical requirement because porcelain firing under He revealed prominent voids and defects within the body of porcelain.


Subject(s)
Dental Porcelain/chemistry , Noble Gases/chemistry , Atmosphere , Materials Testing , Stress, Mechanical , Titanium/chemistry , X-Ray Diffraction
11.
J Dent Sci ; 14(3): 309-317, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31528260

ABSTRACT

BACKGROUND/PURPOSE: Clinically, PMMA resin is extensively used for fabricating provisional FPDs. However, fracture often occurs due to the unsatisfactory mechanical strength, especially within connectors of long-span provisional FPDs. The purpose of this study is to evaluate the fracture load of fiber-reinforced provisional FPDs with various pontic span lengths, and to identify the most suitable span length for fiber-reinforced long-span provisional FPDs. MATERIALS AND METHODS: Fifty-six provisional FPDs with various pontic span lengths were fabricated. Seven samples from each group were reinforced with glass fibers. Unreinforced counterparts served as control. The samples were fixed on the abutments after thermocycling and then received a fatigue test. Subsequently, they were mechanically loaded until fracture, and the initial fracture load and fracture patterns were recorded. Statistical analysis, including two-sample t-test, one-way, two-way ANOVA, Tukey-Kramer HSD post hoc analysis and χ2 test were used to evaluate mechanical performance. RESULTS: The mean fracture load of FPDs with 14 mm pontic span length is significantly higher than the other lengths. The fracture load of each reinforced group is significantly higher than each counterpart control. There is no interaction between two variables, pontic span and fiber reinforcement. With fiber reinforcement, the fracture patterns were altered from catastrophic fracture to bent or partial fracture. But, the fracture patterns were not affected by pontic span. CONCLUSION: The fracture load of acrylic FPDs decreases significantly when pontic span length is greater than 17 mm. Adding glass fibers into long-span provisional FPDs can significantly improve the fracture resistance and fracture patterns.

12.
Arch Gerontol Geriatr ; 79: 27-31, 2018.
Article in English | MEDLINE | ID: mdl-30081329

ABSTRACT

PURPOSE: The objective of this study was to test a hypothesized conceptual model for both the clinical and non-clinical status of oral health and health related quality of life (OHRQoL & HRQoL) among community-dwelling elders. MATERIALS AND METHODS: Study participants (n = 517), who were recruited as part of a Taiwanese elderly community survey, were collected via dental examinations and questionnaires. We collected measures of clinical variables, self-reported symptom status, OHRQoL, nutritional status and HRQoL. The 517 participants were randomly assigned to one of two samples, to provide one training sample for estimation and one testing sample for validation. The path analysis with all observed variables was conducted based on the proposed theoretical model delineating pathways. RESULTS: All of the direct pathways hypothesized by the model were significant. Functional status (OHRQoL measured by OHIP-14T) mediated clinical occlusion, and symptom status mediated nutritional status (MNA) and HRQoL (WHOQOL-BREF). The model accounted for 29% of the variance in HRQoL and demonstrated a good fit with the data. CONCLUSIONS: This conceptual model suggests that OHRQoL, as an important mediator, links clinical conditions, symptom status, nutritional status, and overall HRQoL. Therefore, when therapeutic efforts are made to improve the outcomes for patients with oral diseases, not only can the OHRQoL be enhanced, but also the HRQoL can be improved as a result.


Subject(s)
Models, Theoretical , Oral Health/statistics & numerical data , Quality of Life , Self Report , Aged , Dental Care , Female , Health Services for the Aged , Humans , Independent Living , Male , Middle Aged , Nutritional Status , Surveys and Questionnaires , Taiwan
13.
Kaohsiung J Med Sci ; 34(4): 243-248, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29655414

ABSTRACT

The OSCE is a reliable evaluation method to estimate the preclinical examination of dental students. The most ideal assessment for OSCE is used the augmented reality simulator to evaluate. This literature review investigated a recently developed in virtual reality (VR) and augmented reality (AR) starting of the dental history to the progress of the dental skill. As result of the lacking of technology, it needs to depend on other device increasing the success rate and decreasing the risk of the surgery. The development of tracking unit changed the surgical and educational way. Clinical surgery is based on mature education. VR and AR simultaneously affected the skill of the training lesson and navigation system. Widely, the VR and AR not only applied in the dental training lesson and surgery, but also improved all field in our life.


Subject(s)
Dentistry/methods , Education, Dental/methods , Teaching , Virtual Reality , Academic Performance/statistics & numerical data , Computer Simulation , Humans , Students, Dental
14.
J Dent Sci ; 12(3): 226-232, 2017 Sep.
Article in English | MEDLINE | ID: mdl-30895055

ABSTRACT

BACKGROUND/PURPOSE: Pure titanium (Ti) has many advantages, such as high corrosion resistance and excellent biocompatibility. The mechanical properties of pure Ti are like those of type IV gold alloys. Furthermore, gold alloys can be successfully recast in dental clinics. The aim of this study was to investigate the possibility of recasting pure Ti. MATERIALS AND METHODS: Magnesium oxide (MgO)-based investment that contained a 5 wt. % zirconium dioxide (ZrO2) additive was used. An argon-casting machine (Castmatic-S, Iwatani) was used to recast pure Ti. The first generation and second generation pure Ti (50 wt. % new Ti + 50 wt. % surplus Ti) were used. Five specimens were fabricated and tested. The data were evaluated using two-sample t-test analysis (P < 0.05). RESULTS: The experimental results showed that recasting the Ti did not decrease the marginal accuracy, average surface roughness, Vickers hardness value of the superficial surface, and the thickness of the reaction layer. CONCLUSION: This study clearly showed Ti could be recast when a 5 wt. % ZrO2 additive MgO-based investment was used. This modified investment has the potential for use in clinical applications.

16.
J Biomed Mater Res A ; 103(1): 203-10, 2015 Jan.
Article in English | MEDLINE | ID: mdl-24639027

ABSTRACT

Calcium phosphate cement (CPC) is a widely used bone substitute. However, CPC application is limited by poor bioresorption, which is attributed to apatite, the stable product. This study aims to systematically survey the biological performance of dicalcium phosphate (DCP)-rich CPC. DCP-rich CPC exhibited a twofold, surface-modified DCP anhydrous (DCPA)-to-tetracalcium phosphate (TTCP) molar ratio, whereas conventional CPC (c-CPC) showed a onefold, surface unmodified DCPA-to-TTCP molar ratio. Cell adhesion, morphology, viability, and alkaline phosphatase (ALP) activity in the two CPCs were examined with bone cell progenitor D1 cultured in vitro. Microcomputed tomography and histological observation were conducted after CPC implantation in vivo to analyze the residual implant ratio and new bone formation rate. D1 cells cultured on DCP-rich CPC surfaces exhibited higher cell viability, ALP activity, and ALP quantity than c-CPC. Histological evaluation indicated that DCP-rich CPC showed lesser residual implant and higher new bone formation rate than c-CPC. Therefore, DCP-rich CPC can improve bioresorption. The newly developed DCP-rich CPC exhibited potential therapeutic applications for bone reconstruction.


Subject(s)
Bone Cements , Bone Regeneration , Calcium Phosphates/chemistry , Alkaline Phosphatase/metabolism , Animals , Bone and Bones/enzymology , Mice , Mice, Inbred BALB C , Microscopy, Electron, Scanning
17.
Mater Sci Eng C Mater Biol Appl ; 39: 40-6, 2014 Jun 01.
Article in English | MEDLINE | ID: mdl-24863195

ABSTRACT

In this study, a calcium phosphate cement was developed using tetracalcium phosphate and surface-modified dicalcium phosphate anhydrous (DCPA). This developed injectable bone graft substitute can be molded to the shape of the bone cavity and set in situ through the piping system that has an adequate mechanical strength, non-dispersibility, and biocompatibility. The materials were based on the modified DCPA compositions of calcium phosphate cement (CPC), where the phase ratio of the surface-modified DCPA is higher than that of the conventional CPC for forming dicalcium phosphate (DCP)-rich cement. The composition and morphology of several calcium phosphate cement specimens during setting were analyzed via X-ray diffractometry and transmission electron microscopy coupled with an energy dispersive spectroscopy system. The compressive strength of DCP-rich CPCs was greater than 30MPa after 24h of immersion in vitro. The reaction of the CPCs produced steady final biphasic products of DCPs with apatite. The composites of calcium phosphate cements derived from tetracalcium phosphate mixed with surface-modified DCPA exhibited excellent mechanical properties, injectability, and interlocking forces between particles, and they also featured nondispersive behavior when immersed in a physiological solution.


Subject(s)
Bone Cements/chemistry , Calcium Phosphates/chemistry , Chemical Phenomena , Hydroxyapatites/chemistry , Apatites/chemistry , Bone Substitutes/chemistry , Compressive Strength , Materials Testing , Microscopy, Electron, Scanning , Microscopy, Electron, Transmission , Nanoparticles/chemistry , Spectrometry, X-Ray Emission , Surface Properties , X-Ray Diffraction
18.
Mater Sci Eng C Mater Biol Appl ; 33(6): 3537-44, 2013 Aug 01.
Article in English | MEDLINE | ID: mdl-23706244

ABSTRACT

This study aims to evaluate further the performance of a platelet-rich plasma (PRP) additive incorporated with calcium phosphate bone cement (CPC) in vitro to prove its efficiency as bone graft substitutes and its compatibility to be incorporated into the CPC with other techniques in clinical restoration in vivo. The growth factor release ability and the osteogenic evaluation of PRP, CPC, and PRP/CPC testing groups with 5, 10, and 15 wt.% PRP were compared in vitro. Four groups were measured using non-decalcified staining methods in vivo, which include the testing group of 10 wt.% PRP/CPC selected from the evaluation in vitro, by using both the autograft with rabbit trabecular and CPC-only as comparison groups and the group without grafting material as the control sample. The results obtained through specimen immersion show that growth factor release and alkaline phosphatase activities after osteoprogenitor cell culture had a significantly better effect on 10 and 15 wt.% PRP/CPC than on the other groups in vitro. Analysis results suggest that PRP was still retained in the CPC matrix even after 32 days of immersion. The results in vivo show that the histology of the autograft bone and the control group without grafting material exhibited fibrous connective and adipose tissues, which obviously filled the created cavity even at nine weeks after the operation. Osteoregeneration was more successful in the PRP-additive group, which accumulated bone remodeling than in the other groups. In conclusion, CPC could be a potential carrier with adequate PRP additives that bear a therapeutic potential for enhanced bone tissue regeneration.


Subject(s)
Bone Substitutes/chemistry , Calcium Phosphates/chemistry , Platelet-Rich Plasma , Alkaline Phosphatase/metabolism , Animals , Bone Marrow Cells/cytology , Bone Substitutes/pharmacology , Bone Substitutes/therapeutic use , Bone Transplantation , Bone and Bones/metabolism , Bone and Bones/pathology , Cell Line , Mesenchymal Stem Cells/cytology , Mesenchymal Stem Cells/drug effects , Mesenchymal Stem Cells/metabolism , Mice , Mice, Inbred BALB C , Platelet-Derived Growth Factor/metabolism , Rabbits , Transplantation, Autologous
19.
Angle Orthod ; 83(5): 920-6, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23560978

ABSTRACT

Concurrent impaction and transposition of maxillary anterior teeth is uncommon and poses a challenge for dentists. Early diagnosis and management of eruption disturbances benefits esthetic and functional outcomes. This article describes the treatment of a teenager who had impactions of the left maxillary central incisor and canine as well as ipsilateral canine-lateral incisor transposition. Treatment alternatives and effective orthodontic techniques are delineated. To optimize the treatment results, the impacted maxillary canine was surgically exposed and orthodontically distalized with an innovative cantilever. Subsequently, the deeply impacted maxillary central incisor was uncovered and orthodontically mesialized into the arch. Finally, the displaced maxillary lateral incisor was brought into its normal position. The combined surgical-orthodontic approach resolved a difficult clinical issue and avoided additional restorations. An esthetic, functional outcome was achieved and satisfied the patient.


Subject(s)
Cuspid/abnormalities , Incisor/abnormalities , Malocclusion, Angle Class I/rehabilitation , Maxilla/abnormalities , Tooth, Impacted/surgery , Adolescent , Cephalometry , Cone-Beam Computed Tomography , Female , Humans , Tooth, Impacted/diagnostic imaging , Tooth, Impacted/rehabilitation
20.
Qual Life Res ; 22(7): 1665-74, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23180165

ABSTRACT

PURPOSE: The objective was to determine the responsiveness properties of the Oral Health Impact Profile (OHIP) short-forms and 36-item Short-Form (SF-36) in complete denture treatment, and further to evaluate the association between patients' satisfaction and improvements in oral and general health-related quality of life (OHRQoL and HRQoL) after fitting of new, complete dentures. METHODS: Study data were obtained from the 'Dentures for the Elders through Public Funding' study conducted in Kaohsiung County. A total of 224 subjects received denture treatments with 6-month follow-up and pre-/post-treatment interviews by questionnaire. The OHIP and SF-36 were used to measure OHRQoL and HRQoL. In addition, specific questions investigating seven aspects of patients' satisfaction were used to measure the patients' perceptions of complete denture success. The responsiveness of all outcome measures and their dimensions were assessed by effect size (ES). Multivariable analysis was used to examine the association between patients' satisfaction and OHIP/SF-36 while adjusting for demographic characteristics. RESULTS: There were improvements with regard to the 'physical pain' (ES = 0.19) and 'psychological discomfort' (ES = 0.42) dimensions of the Taiwanese short-form OHIP (OHIP-14T) after new complete denture treatment, but only improvement in the 'general health' (ES = 0.17) dimension in the SF-36 measure. Patients satisfied with 'comfort' and 'ease of cleaning' of their new dentures were significantly associated with the improvement of the OHIP-49 and OHIP-14T. CONCLUSIONS: This study suggests that denture treatments are associated with improvements of OHRQoL, but not in HRQoL. Furthermore, patients' satisfaction was significantly associated with responsiveness of OHRQoL but less significantly associated with responsiveness of HRQoL.


Subject(s)
Dentures/psychology , Personal Satisfaction , Quality of Life , Surveys and Questionnaires , Aged , Aged, 80 and over , Denture, Complete/psychology , Female , Follow-Up Studies , Health Status , Humans , Interviews as Topic , Male , Multivariate Analysis , Oral Health , Outcome Assessment, Health Care , Patient Satisfaction , Reproducibility of Results , Sickness Impact Profile , Taiwan
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