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Org Biomol Chem
; 11(20): 3393-9, 2013 May 28.
Article
in English
| MEDLINE
| ID: mdl-23563191
ABSTRACT
Spirolactones, spirotetrahydrofurans, and spiropyrrolidines containing a vicinal cis-diol adjacent to the spiro-carbon center are prepared by one-pot epoxidation/spirocyclization of cyclohex-2-en-1-ols bearing an ester, alcohol, or amide functional side chain at the C(3) position of the ring.