Effects of jianpi herbal suppository on hemorheology and CD62p in patients with ulcerative colitis.

OBJECTIVE: To compare the effects of a Chinese herbal suppository (Jianpi suppository) and Western Medicine (mesalazine) on hemorheology and CD62p in patients with ulcerative colitis (UC). METHODS: In a randomized trial, 120 mild to moderate UC patients were randomly divided into two equal groups. The Jianpi suppository group used Chinese herbal suppository rectally, while the mesalazine group was treated with mesalazine tablets orally. Two 15-day courses of treatment were carried out in both groups. Changes in the hemorheology and CD62p indices in patients were observed. RESULTS: The hemorheology and CD62p indices in the Jianpi suppository group decreased significantly more than those of the mesalazine group. CONCLUSION: Jianpi suppository is effective in improving the hypercoagulability of UC patients, and therefore may be worth using in clinical practice.

How to achieve deep remission in treatment of inflammatory bowel disease.

OBJECTIVE: This article investigates the methods of achieving deep remission of inflammatory bowel disease (IBD). METHODS: Increasing recognition of the concept of quality of care is contributing to the evolution of treatment goals in patients with IBD from clinical response and remission (symptom control) toward deep remission. A change in the treatment goal requires a change in the treatment strategy. Optimization of conventional therapy, early treatment, use of the Lemann score, performance of double-balloon endoscopy, treatment using Traditional Chinese Medicine, and good communication between physicians and patients are needed to attain deep remission. RESULTS: The above-mentioned methods can help to achieve deep remission. CONCLUSION: Using the avoeve methods, it will be possible to improve the prognoses of patients with IBD by minimizing complications and bowel damage and thereby changing the course of the disease.