ABSTRACT
A novel way of synthesizing anthranilic esters was developed via Pd-catalyzed dehydrogenative/decarbonylative coupling between anilides and glyoxylates.
ABSTRACT
Nontransition metal-catalyzed synthesis of 2-aryl benzothiazoles was achieved through K(2)S(2)O(8)-mediated oxidative condensation of benzothiazoles with aryl aldehydes. The same transformation can also be effected when the aryl aldehydes were replaced with phenylglyoxylic acids.
Subject(s)
Aldehydes/chemistry , Benzothiazoles/chemical synthesis , Glyoxylates/chemistry , Mandelic Acids/chemistry , Catalysis , Molecular Structure , Oxidation-Reduction , Potassium Compounds/chemistry , Stereoisomerism , Sulfates/chemistryABSTRACT
A Pd-catalyzed decarboxylative coupling of thiazoles and benzoxazole with various substituted benzoic acids is developed. The reaction is compatible with both electron-rich and electron-poor benzoic acids. It can also be extended to the synthesis of polyfluoro-substituted biaryls using polyfluorobenzenes as the starting materials.
Subject(s)
Benzoates/chemistry , Benzoxazoles/chemistry , Fluorobenzenes/chemistry , Palladium/chemistry , Thiazoles/chemistry , Catalysis , Decarboxylation , Molecular Structure , StereoisomerismABSTRACT
A one-step preparation of xanthones via Pd-catalyzed annulation of 1,2-dibromoarenes and salicylaldehydes was developed.
Subject(s)
Aldehydes/chemistry , Palladium/chemistry , Xanthones/chemistry , Catalysis , Cyclization , Xanthones/chemical synthesisABSTRACT
An efficient oxidative Mannich reaction between tertiary amines and unmodified methyl ketones has been developed, using copper salts as the catalyst and O(2) as the oxidant.
