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2.
J Am Acad Dermatol ; 82(3): 723-728, 2020 Mar.
Article in English | MEDLINE | ID: mdl-31654665

ABSTRACT

Frontal fibrosing alopecia (FFA) is a cicatricial alopecia of unknown etiology. The incidence of FFA appears to be increasing with time, leading to suspicion of a possible environmental trigger. Observational studies have reported a positive correlation between facial sunscreen use and FFA. This finding raises the question of whether sunscreen use plays a role in disease development. In this article, we review the available literature on the association of sunscreen with FFA. There is insufficient evidence to establish a direct causal relationship between sunscreen and FFA. Further studies are required to better characterize the role of sunscreen and the environment in the pathogenesis of this unique disease.


Subject(s)
Alopecia/chemically induced , Cicatrix/chemically induced , Sunscreening Agents/adverse effects , Alopecia/complications , Cicatrix/complications , Forehead , Humans
3.
Am J Clin Dermatol ; 18(5): 643-650, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28510141

ABSTRACT

Sunscreens have been widely used by the general public for their photoprotective properties, including prevention of photocarcinogenesis and photoaging and management of photodermatoses. It is important to emphasize to consumers the necessity of broad-spectrum protection, with coverage of both ultraviolet A (320-400 nm) and ultraviolet B (290-320 nm) radiation. This review discusses the benefits of sunscreen, different ultraviolet filters, sunscreen regulations and controversies, the importance of broad-spectrum protection, issues of photostability and formulation, and patient education and compliance.


Subject(s)
Carcinogenesis/drug effects , Skin Aging/drug effects , Sunscreening Agents/therapeutic use , Ultraviolet Rays/adverse effects , Carcinogenesis/radiation effects , Consumer Product Safety/legislation & jurisprudence , Environmental Pollution/prevention & control , Humans , Patient Compliance , Patient Education as Topic , Skin Aging/radiation effects , Sunscreening Agents/adverse effects , Sunscreening Agents/radiation effects , Sunscreening Agents/standards
4.
JAMA Dermatol ; 153(3): 304-308, 2017 03 01.
Article in English | MEDLINE | ID: mdl-28114650

ABSTRACT

Importance: Sun-protective behavior affects skin cancer prevention. Shade works by physically shielding skin from direct harmful UV rays; however, skin may still remain exposed to reflected and indirect UV rays. There is no current standard metric to evaluate shade for its effectiveness in sun protection, and there is insufficient clinical evidence that a beach umbrella alone can provide adequate sun protection. Objective: To directly measure sunburn protection offered by a standard beach umbrella compared with that provided by sunscreen with a high sun protection factor under actual use conditions. Design, Setting, and Participants: A single-center, evaluator-blinded, randomized clinical study was conducted from August 13 to 15, 2014, in Lake Lewisville, Texas (elevation, 159 m above sea level), among 81 participants with Fitzpatrick skin types I (n = 1), II (n = 42), and III (n = 38). Participants were randomly assigned to 2 groups: 1 using only a beach umbrella, and the other using only sunscreen with a sun protection factor of 100. All participants remained at a sunny beach for 3½ hours at midday. Clinical sunburn evaluation of each individual for all exposed body sites was conducted 22 to 24 hours after sun exposure. Interventions: The shade provided by a beach umbrella or protection provided by sunscreen with a sun protection factor of 100. Main Outcomes and Measures: Sunburn on all exposed body sites 22 to 24 hours after sun exposure. Results: Among the 81 participants (25 male and 56 female; mean [SD] age, 41 [16] years) for all body sites evaluated (face, back of neck, upper chest, arms, and legs), the umbrella group showed a statistically significant increase in clinical sunburn scores compared with baseline and had higher postexposure global scores than the sunscreen group (0.75 vs 0.05; P < .001). There was a total of 142 sunburn incidences in the umbrella group vs 17 in the sunscreen group. Thirty-two of the 41 participants (78%) in the umbrella group showed erythema in 1 or more sites vs 10 of the 40 participants (25%) in the sunscreen group (P < .001). Neither umbrella nor sunscreen alone completely prevented sunburn. Conclusions and Relevance: A beach umbrella alone may not provide sufficient protection for extended UV exposure. It is important to educate the public that combining multiple sun protection measures may be needed to achieve optimal protection. Trial Registration: isrctn.org Identifier: ISRCTN19177299.


Subject(s)
Protective Devices , Sun Protection Factor , Sunburn/etiology , Sunburn/prevention & control , Sunscreening Agents/administration & dosage , Adult , Arm , Bathing Beaches , Face , Female , Humans , Leg , Male , Middle Aged , Neck , Single-Blind Method , Sunburn/diagnosis , Sunlight/adverse effects , Thorax
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